Despite recent advancements in multidisciplinary treatments, the overall survival and quality of life of patients with advanced head and neck squamous cell carcinoma (HNSCC) have not improved significantly over the past decade. Molecular targeted therapies, which have been addressed and advanced by the concept of "oncogene addiction", have demonstrated only limited successes so far. To explore ...

Extravasation of bile into the peritoneal cavity of infants and children, unassociated with trauma, has been described sufficiently rarely in the past to merit the reporting of two further cases. The term 'bile peritonitis' is misleading as a description of the clinical picture seen in these particular infants. The condition is essentially an escape of bile following rupture of some component o...

We analyze here the structure of non-radial nonspacelike geodesics terminating in the past at a naked singularity formed as the end state of inhomogeneous dust collapse. The spectrum of outgoing nonspacelike geodesics is examined analytically. The local and global visibility of the singularity is also examined by integrating numerically the null geodesics equations. The possible implications of...

− Burkina Faso has experienced quite significant aggregate growth over the past two decades, but the economy has done a bad job in transforming that growth into poverty reduction. The key bottleneck preventing people from escaping poverty in large numbers is the still very high population growth in conjunction with the absence of major technological change in agriculture and any significant str...

We construct several new classes of transcendental entire functions, f , such that both the escaping set, I ( f ), and the fast escaping set, A( f ), have a structure known as a spider’s web. We show that some of these classes have a degree of stability under changes in the function. We show that new examples of functions for which I ( f ) and A( f ) are spiders’ webs can be constructed by comp...

Nowadays, piracy as one of crimes at sea has formed in different ways compared to the historical counterparts. On past, act consisted first approaching ship, then fighting it, and finally seizing it before escaping another vessel. Meanwhile, recent times, more sophisticated kinds are launching their assaults with help cutting-edge technology. However, due UNCLOS's restricted definition piracy, ...