The observation at necropsy of a patent ductus arteriosus in patients dying in the neonatal period is virtually universal. As a rule this observation is of no practical significance since death is caused by one of a large group of conditions not necessarily related to the cardiovascular system. Occasionally the finding is of importance, as in two male infants, with widely patent ducti, whom we ...

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BACKGROUND The prophylactic administration of indomethacin reduces the frequency of patent ductus arteriosus and severe intraventricular hemorrhage in very-low-birth-weight infants (those with birth weights below 1500 g). Whether prophylaxis with indomethacin confers any long-term benefits that outweigh the risks of drug-induced reductions in renal, intestinal, and cerebral blood flow is not kn...

BACKGROUND Diagnosis of extracardiac intrathoracic vascular anomalies is of clinical importance, but remains challenging. Traditional imaging modalities, such as radiography, echocardiography, and angiography, are inherently limited by the difficulties of a 2-dimensional approach to a 3-dimensional object. We postulated that accurate characterization of malformations of the aorta would benefit ...

Congenital aortic or subaortic stenosis was demonstrated in 7 of 50 patients with patent ductus arteriosus. In addition to the murmurs characteristic of each lesion and diagnostic carotid artery pulse tracings, inordinate enlargement of the left ventricle with a small shunt through the patent ductus should suggest involvement of the aortic valve. The clinical findings associated with this combi...

OBJECTIVES This study was designed to assess the safety, efficacy, medium-term outcome, and complications of patent ductus arteriosus (PDA) stenting in duct-dependent pulmonary circulation. BACKGROUND Patent ductus arteriosus stenting has been proposed as an alternative to surgical shunt on account of postoperative morbidity and complications of surgical shunting. METHODS Between April 2000...

BACKGROUND The patent ductus arteriosus (PDA) is an important problem in premature infants. Surgical PDA ligation is usually only be considered when medical treatment has either failed or was contraindicated. The aims of our study were to determine the mortality and morbidity following patent ductus arteriosus ligation in premature infants, and whether prostaglandin synthetase inhibitor (PSI) u...

INTRODUCTION Kawasaki disease is regarded as systemic vasculitis. Many experts believe that not only coronary arteries but also other small arteries are involved during the period of systemic inflammation. However, the evidence to support this point view is limited. CASE PRESENTATION We report the case of a one-year-four-month-old Taiwanese girl whose patent ductus arteriosus was incidentally...

We present a rare case of main pulmonary artery stenosis secondary to protruding fibrous material in the main pulmonary artery associated with patent ductus arteriosus. A 1-month-old baby boy manifested cardiac murmur. Echocardiogram showed circumferential high echogenic mass inside the main pulmonary artery with pressure gradient of 49 mmHg and patent ductus arteriosus. The mass did not regres...