UNLABELLED A comprehensive, SPECT-based, patient-specific 3-dimensional (3D) dosimetry analysis has been performed using 3D-ID, a previously developed software package. The role of the total-body tumor burden, individual lesion size, tumor absorbed dose, and the spatial distribution of the absorbed dose on response and on the time course of tumor shrinkage has been examined in patients with lym...

BACKGROUND The decreasing image quality in heavier patients can be compensated by administration of a patient-specific dose in myocardial perfusion imaging (MPI) using a cadmium zinc telluride-based SPECT camera. Our aim was to determine if the same can be achieved when using a conventional SPECT camera. METHODS 148 patients underwent SPECT stress MPI using a fixed Tc-99m tetrofosmin tracer d...

Background  It is remain a main concern that pediatric chest radiographies contribute to the significant radiation exposure to the thyroid gland as a more susceptible organ to radiation induced cancer. The aim of this study was to evaluate the entrance surface dose (ESD) of pediatric chest radiography compared to the diagnostic reference levels (DRL) and evaluation the efficacy of the lead (Pb)...

An increase in the number of diagnostic procedures using ionizing radiation (computed tomography, interventional procedures, and use nuclear medicine) results an exposure and, consequently, collective individual doses to patients.
 Diagnostic studies from international professional community are extensively focusing on issues such as management dose optimization. Worldwide practice can res...

objective(s) as there are conflicting findings regarding the clearance-dose and patient characteristics relationships for valproic acid (vpa), this study was conducted to investigate the relationship between patient demographic characteristics, vpa dosage and the drug clearance in adult iranian patients. materials and methods patients (n= 47) were either on monotherapy with vpa or were under co...

Introduction: The CT Provide high quality images, especially in low-contrast soft tissue, are another advantage. Along with all the benefits that the CT scans which have, the patient dose of this modality is much greater than other methods. As a result, medical imaging community must ensure that the benefits of radiological examination for each patient are higher than related r...

Background: In Helical Tomotherapy (HT), the scaling factor (SF) is the time in seconds that each leaf viewing a target would need to be open to deliver the prescribed dose. The SF is patient-specific and is used to calculate the rotational period of the gantry, and the total treatment time (TTT) of the HT. The SF is generally difficult to estimate. Currently, it takes about one hour t...

We obtained cell preparations containing greater than 95% neutrophils from freshly drawn bovine blood. The cells were suspended in sucrose and disrupted in a Dounce homogenizer, and the postnuclear supernate was fractionated by zonal differential sedimentation and by isopycnic equilibration. The subcellular fractions were characterized biochemically by testing for marker enzymes and other const...