Background and objective:Breast cancer is the most common malignancy among women. The Neoadjuvant chemotherapy is the treatment of choice for non-operable tumors. The Ki67 is a proliferation marker that can be used to predict the therapeutic response to chemotherapy and the patients' prognosis. Methods: This retrospective study was carri...

Background: Due to their similar routes of transmission, human immunodeficiency virus (HIV) and hepatitis B virus (HBV) co-infection occurs considerably. HBV infection progresses more rapidly in HIV-infected patients. Therefore, HBV vaccination of all non-immune HIV infected patients is recommended. On the other hand, HIV-infected subjects have suboptimal responses to HBV vaccine. In this study...

Background: Psoriasis is a chronic disease with multiple biochemical and vascular abnormalities. Several studies have evaluated circulating levels of vascular endothelial growth factor (VEGF) in psoriasis, but none of them evaluated it after reaching a PASI-75 response, as a practical treatment goal. The aim of this study was to evaluate serum levels of VEGF in moderate to severe psoriatic pati...

background: gastric outlet obstruction (goo) due to peptic stricture is one of three known complications of peptic ulcer disease and usually requires therapeutic intervention for symptoms relief. after benjamin sb who primarily used balloon dilation for treatment of goo in 1982, some series has been published investigating procedure efficacy with different results. the purpose of this study is ...

background: patients with symptomatic malignant pleural effusion (mpe) may gain profit from pleurodesis for relief of dyspnea and in preventing the accumulation of fluid or air in the pleural space. pleurodesis methods are palliative and regard the patient's symptoms and underlying disease condition that are different. the purpose of this study was to assess the efficacy of bleomycin in th...

serum alpha-tocopherol of98(62 male and 36 female) cancer patients and 30 (13 male and 17 female) control healthy subjects was investigated. the cancer patients showed a significantly low level of alpha-tocopherol as compared to control healthy subjects. also, significantly higher levels of serum alpha-tocopherol were found in complete remission patients as compared to the partial response pati...

context: to evaluate treatment success and hypothyroidism following main methods of radioiodine therapy of toxic nodular goiter (tng); calculated versus fixed dose and high versus low dose of radioiodine. evidence acquisitions: we searched medline and scopus databases from inception till july 2013, for clinical trials that compared two different methods of radioiodine administration in tng. the...

objective neuropsychological impairment is an important co-morbidity of chronic epilepsy. the aim of this study was to determine the state of the cognitive and motor development of patients with refractory epilepsy. materials & methods  we studied 150 consecutive children with epilepsy who were referred to mofid children hospital, a third level public referral university hospital in tehran, ira...

this is a retrospective study on clinical course and treatment response of patients with thyroid hot nodule, referred to nuclear medicine department of shariati hospital from 1360 to 1377. from the total 58 patients with average age of 43 yr and incidence peak of 40 yr, 81% were female and 19% were male. 64% of the patients were thyrotoxic and 36% were euthyroid at presentation. thyrotoxic symp...