objectives: in this study, the relation of late-life body mass index (bmi) and waist circumference with incident dementia risk was investigatedin a group of iranian elderly peopel. methods & materials: in cross-sectional present study 107 elderly residents of the kahrizak charity foundation aged 80 and older were participated. dementia was assessed using mini-mental state examination questionna...

Background: Senile dementia is the most common kind of dementia with considerable social and economic costs. Since the nature of disease is multi-pathological, current treatments cannot cover all aspects of the disease. Recently, scientific considerations have focused on the role of natural products, especially those with traditional backgrounds. Objective: to review natural treatments of demen...

Dementia in general and Alzheimer's disease in particular is increasingly seen in association with autoimmunity being causatively or supportively involved in the pathogenesis. Besides classic autoantibodies (AABs) present in dementia patients, there is the new autoantibody class called functional autoantibodies, which is directed against G-protein coupled receptors (GPCRs; GPCR-AABs) and are se...

The assessment and treatment of psychiatric symptoms in persons with cognitive dysfunction are becoming increasingly important. Prevalence estimates of dementia in the United States range from 5% in those aged 71 to 79 years to 25% to 50% in those 90 or older. Up to 90% of patients with dementia have psychiatric comorbidities.1,2 Physicians who treat patients with dementia must remember that de...

BACKGROUND The mechanisms behind the association of atrial fibrillation (AF) and dementia are unknown. We previously found a significantly increased risk of dementia in AF patients taking warfarin with a low percentage of time in therapeutic range. The purpose of this study was to determine the extent to which AF itself increases dementia risk, in addition to long-term anticoagulation exposure....

OBJECTIVE To test predictions that frontotemporal dementia and semantic dementia give rise to distinct patterns of behavioural change. METHODS An informant based semistructured behavioural interview, covering the domains of basic and social emotions, social and personal behaviour, sensory behaviour, eating and oral behaviour, repetitive behaviours, rituals, and compulsions, was administered t...

BACKGROUND/AIMS Orthostatic hypotension (OH) and QTc prolongation have potentially important prognostic and therapeutic consequences but have rarely been studied in patients with mild dementia. METHODS Patients with mild dementia were diagnosed according to consensus criteria after comprehensive standardized assessment. OH and QTc were assessed using standardized criteria. RESULTS OH was si...

Longitudinal measurements of cognitive ability measured by serial testing using the Cognitive Capacity Screening Examination (CCSE) were correlated with cerebral blood flow (CBF) throughout (mean ± SD) 19.9 ± 12.6 months among 57 patients with multi-infarct dementia, 17 with dementia of the Alzheimer's type, 10 with both, and among 32 age-matched elderly normal controls. Longitudinal CCSE and C...

Longitudinal measurements of cognitive ability measured by serial testing using the Cognitive Capacity Screening Examination (CCSE) were correlated with cerebral blood flow (CBF) throughout (mean +/- SD) 19.9 +/- 12.6 months among 57 patients with multi-infarct dementia, 17 with dementia of the Alzheimer's type, 10 with both, and among 32 age-matched elderly normal controls. Longitudinal CCSE a...

Globally, dementia affects 47.5 million people, making it a significant health concern. The growing number of people with is posing challenge to the care systems. Dementia complicated progressive syndrome which characterized by impairment cognition, changes in personality leading impeded daily life activities. poses burden patients, their families society and healthcare systems context cost car...