Software patterns are computing artifacts used to document knowledge that may be reused during software development process. There are several types of patterns, such as analysis, design, and architectural, among others. Design patterns are the most well known by designers, but many of them are described in books and scientific papers, a recurring way of documenting patterns that limits their r...

Molecular databases are routinely screened for compounds that most closely resemble a molecule of known biological activity to provide novel drug leads. It is widely believed that three-dimensional molecular shape is the most discriminating pattern for biological activity as it is directly related to the steep repulsive part of the interaction potential between the drug-like molecule and its ma...