The present study investigated the beneficial role of selenium (Se) in protecting oilseed rape (Brassica napus L.) plants from cadmium (Cd+2) and lead (Pb+2) toxicity. Exogenous Se markedly reduced Cd and Pb concentration in both roots and shoots. Supplementation of the medium with Se (5, 10, and 15 mg kg-1) alleviated the negative effect of Cd and Pb on growth and led to a decrease in oxidativ...

Phenylacetate (PA) and phenylbutyrate (PB) are aromatic fatty acids that are presently undergoing evaluation as potential antineoplastic agents. In vitro, PA and PB cause differentiation or growth inhibition of malignant cells. Clinical trials of these drugs as single agents indicate that they are not myelosuppressive; therefore, combinations with other chemotherapy agents may be possible. The ...

Elemental abundances and Nd and Pb isotope ratios were determined on samples from the carbonate-free, clay-size fractions of sediments from intervals above, within, and below Heinrich event 2 (H-2) in core HU87-9 from the Northwest Labrador Sea slope. In HU87-9, rare-earth element (REE) distributions and elemental concentrations within the H-2 event are distinct from those outside this event. e...

The present study was designed to investigate the effects of Pb(2+) on modulation of synaptic transmission by nicotinic receptors (nAChRs) in the rat hippocampus. To this end, inhibitory and excitatory postsynaptic currents (IPSCs and EPSCs, respectively) were recorded by means of the whole-cell mode of the patch-clamp technique from rat hippocampal neurons in culture. Acetylcholine (ACh, 1 mM;...

The structure of the title compound, [Pb(2)(C(5)H(3)N(2)O(2))(4)(H(2)O)(6)]·2H(2)O, is composed of dimeric mol-ecules in which two symmetry-related Pb(2+) ions are bridged by a pair of two pyridazine-4-carboxyl-ate ligand mol-ecules via both heterocyclic N atoms and two water O atoms. Each Pb(2+) ion is also coordinated by two carboxyl-ate O atoms and three water O atoms, leading to a highly ir...

A fluoroionophore sensor, N-[4-(1-pyrene)butyroyl]-L-tryptophan (PLT), has been reported. It can distinguish lead ion from other 12 metal ions via forming a pyrene dimer and it exhibits a very high sensitivity (0.15 microM) in aqueous solution (Chem. Commun., 2006, 2702). When the indole moiety in PLT was changed to benzene, in forming a new fluoroionophore of N-[4-(1-pyrene)butyroyl]-L-phenyla...

A pattern of electrical stimulation based on 2 prominent physiological features of the hippocampus, complex spike discharge and theta rhythm, was used to induce lasting increases in responses recorded in area CA1 of hippocampal slices maintained in vitro and from the hippocampus of behaving rats. This effect, termed primed burst (PB) potentiation, was elicited by as few as 3 stimuli delivered t...

The title compound, [PbCl(2)(C(17)H(9)NO(3))](n), was synthesized by the hydro-thermal reaction of PbCl(2) and liriodenine. The lead(II) atom has a distorted octa-hedral environment made up of the O and N atoms of the liriodenine ligand [Pb-O 2.666 (4) Å, Pb-N 2.587 (5) Å, O-Pb-N 61.78 (14)°] and four bridging chloro ligands, which link the complex mol-ecules into infinite chains along the a ax...

The Pb atom in the polymeric title compound, {[Pb(C(13)H(9)N(3)O(2))]·CH(3)OH}(n), is five-coordinated within an N(2)O(2) donor set and a lone pair of electrons, as the N-isonicotinamido-salicylaldiminate ligand coordinates the Pb(II) atom via the O,N,O'-donors and simultaneously bridges a neighbouring Pb atom via the pyridine N atom; the coordination geometry is based on a trigonal bipyramid w...

The title compound, [Pb(2)(C(7)H(5)O(2))(2)(NO(3))(2)(C(12)H(8)N(2))(2)(H(2)O)(2)], crystallizes as a dinuclear centrosymmetric dimer containing two Pb(II) atoms bridged by two benzoate ligands. Each Pb(II) atom is seven-coordinated by a water mol-ecule, a nitrate anion, a 1,10-phenanthroline (phen) ligand and two benzoate anions. The crystal packing is stabilized by O-H⋯O hydrogen bonds and by...