BACKGROUND Prolactin is a hormone; in addition to it known roles, it has immunomodulatory effects on lymphocytes maturation and immunoglobulins production. Hyperprolactinemia has been demonstrated in various autoimmune diseases such as systemic lupus erythematosus, rheumatoid arthritis, type I diabetes mellitus, and Graves' disease. In view of the prolactin immunomodulatory roles, studying prol...

Pemphigus vulgaris is a rare, life-threatening, autoimmune bullous disease. After decades of systemic corticosteroids and corticosteroid-sparing immunosuppressants being used to control the disease, efficacy rituximab has been shown in randomized controlled studies. Hence constitutes first-line treatment for mild moderate-to-severe pemphigus according most recent European S2K guideline. Despite...

IMPORTANCE To our knowledge, these are the first reports of bloodstream infections by Trichosporon inkin in patients with pemphigus. OBSERVATIONS Trichosporon inkin, a novel organism causing bloodstream infection, was detected in 2 patients with pemphigus. An elderly man with pemphigus foliaceus died despite treatment with liposomal amphotericin B, 3 mg/kg/d, and a young girl with pemphigus v...

Pemphigus vulgaris (PV) is a chronic autoimmune blistering disease of the skin and mucous membranes that affects older individuals. The disease rarely affects children and adolescent patients. The first manifestation of PV appears in the oral mucosa in the majority of patients, followed by cutaneous lesions. The diagnosis is based on clinical findings and laboratory analyses, and it is usually ...

OBJECTIVE The purpose of the study was to evaluate the clinical presentation of pemphigus vulgaris in the oral cavity. STUDY DESIGN A retrospective study of 71 cases of pemphigus vulgaris obtained over a period of 7 years from 1st January 2001 to 31st December 2007 in the Department of Oral Pathology, Government Dental College and Department of Dermatology, Government Medical College, Calicut...

Pemphigus vulgaris is an autoimmune disorder which presents with painful mucocutaneous blisters and erosions. On the skin, they are flaccid bullae or erosions, and on the mucosa, they present as erosions. This disease is rare but is devastating to those who have it; it also is related—perhaps genetically—to other autoimmune conditions. This is to say that a patient can develop pemphigus vulgari...

BACKGROUND Intravenous immunoglobulin rapidly decreases serum levels of intercellular antibodies in patients with pemphigus vulgaris. However, little is known about the effects of this therapy on antibodies directed specifically against desmoglein 1 and desmoglein 3 and on the IgG subclasses of these antibodies. This study was conducted to study the effect of intravenous immunoglobulin therapy ...

Le pemphigus vulgaris est une maladie dermatologique chronique d'origine auto-immune. Il atteint la peau ou les muqueuses avec des lésions à type de bulles ou de croûtes. Il fait partie des maladies appelées dermatoses bulleuses auto-immunes. La fréquence de l'atteinte otorhinolaryngologique n'est pas précisée au cours du pemphigus vulgaris. Une atteinte isolée de l'oreille est rare. Patiente â...

Pemphigus Vulgaris (PV) is an autoimmune intraepidermal blistering disorder of the skin and mucous membranes.1 Oral lesions have been reported as an initial manifestation of the disease in 50% of cases.2 A case of pemphigus vulgaris is hereby described occurring in a 55-year-old man with a chief complaint of 3-month history of chronic oral erosions and burning sensation. He had several superfic...