gisol that shows a high hosology with the products of Aspergilius nidulans r!jC gene i3) and leurospora crassa try-l gene 4) (71.5% and 630. respectively), strongly suggesting that: fi! the protein is a trifunctional polypepride containing the glutraine aslidc transferase GAT), indoleglycerolphophate synchase IGPS) and phosphoribosylanthranilate isoserase PRAII activities of the tryptophan bios...

Penicillium chrysogenum utilizes phenylacetic acid as a side chain precursor in penicillin G biosynthesis. During industrial production of penicillin G, phenylacetic acid is fed in small amounts to the medium to avoid toxic side effects. Phenylacetic acid is taken up from the medium and intracellularly coupled to 6-aminopenicillanic acid. To enter the fungal cell, phenylacetic acid has to pass ...

The kinetics of penicillin production by Penicillium chrysogenum Wis 54-1255 in a glucose-limited chemostat and in batch cultures are reported. The specific production rate of penicillin, q(pen) (units per milligram of dry weight per hour) was independent of specific growth rate over the range 0.014 to 0.086 hr. Growth was stopped by restricting the glucose supply to the "maintenance ration," t...

Fungi commonly known for diseases generating and fermentation agents, apart from this some fungi show biodegradation agents. Pesticides are used for controlling plant diseases but when spraying the pesticides only 40% goes at target and the rest in soil environment. So the soil be contaminated and as a result of this useful microflora are affected and soil fertility decline. So, some fungi test...

Metabolic profiling and structural elucidation of novel secondary metabolites obtained from derived deletion strains of the filamentous fungus Penicillium chrysogenum were used to reassign various previously ascribed synthetase genes of the roquefortine/meleagrin pathway to their corresponding products. Next to the structural characterization of roquefortine F and neoxaline, which are for the f...