AIM To explore the mechanism of chronic renal failure (CRF)-related erectile dysfunction (ED). METHODS CRF experimental models were established by 5/6 nephrectomy from male Sprague-Dawley rats. Both the rats from the control group (NCRF group, n=6) and the experimental group (CRF group, n=30) were injected with a low dose (80 microg/kg) of apomorphine in the 12th week after resection surgery ...

AbstrAct Aim: To evaluate diagnosis and prediction of ED by using nocturnal penile tumescence, rigidity (NPTR) combined with audiovisual sexual stimulation (AVSS) and Sildenafil. Materials and Methods: Multicentre study was conducted. Penile rigidity was recorded by NPTR test during 1 hour. AVSS test was performed in 3 steps; First step involved no medical treatment whereas the 2nd and 3rd step...

Erectile dysfunction affects a large segment of the male population, and in most cases impaired relaxation of the smooth muscle cells in the corpus cavernosum and the penile arteries is a factor. Sildenafil, a relatively specific vasodilator of the penile circulation, has revolutionized the treatment of impotence. This article describes the biochemistry of erection, outlines the problems that c...

Male erectile dysfunction (MED) is defined as the “inability to achieve or maintain an (penile) erection adequate for sexual satisfaction” (National Institutes of Health Consensus Statement, 1993). Erectile dysfunction occurs in varying degrees in an estimated 20 to 30 million U.S. men and is associated with adverse effects on quality of life, particularly personal well being, family, and socia...

Male erectile dysfunction (MED) is defined as the “inability to achieve or maintain an (penile) erection adequate for sexual satisfaction” (National Institutes of Health Consensus Statement, 1993). Erectile dysfunction occurs in varying degrees in an estimated 20 to 30 million U.S. men and is associated with adverse effects on quality of life, particularly personal well being, family, and socia...

PURPOSE We investigated erectile and ejaculatory function after penile prosthesis implantation. MATERIALS AND METHODS A total of 121 patients were enrolled in the surgery group (SG) and 120 patients in the nonsurgery group (NSG). All subjects were evaluated by use of the following questionnaires: the erection function and intercourse satisfaction domains of the International Index of Erectile...

The generation of nitric oxide (NO) in penile erectile tissue and the subsequent elevation of cyclic GMP (cGMP) levels are important for normal penile erection. Current treatments of erectile dysfunction elevate either cGMP levels by blocking cGMP degrading phosphodiesterase 5 or cyclic AMP (cAMP) levels by intrapenile injection of prostaglandin E1. The molecular target or targets of cGMP in er...

INTRODUCTION Priapism is an uncommon disorder of involuntary prolonged erection beyond sexual excitement or desire. Herein, we present a rare case of priapism resulting from traditional circumcision under regional anesthesia with dorsal penile nerve block by xylocaine, which was successfully treated by intracavernosal injection of metaraminol bitartrate. CASE DESCRIPTION A 37-year-old man vis...

PURPOSE This study was designed to evaluate the efficacy of medical treatment of Peyronie's disease. MATERIALS AND METHODS A total of 109 patients with Peyronie's disease who had been treated from January 2011 to December 2014 were retrospectively reviewed in this study. Forty-four patients (Group 1) were treated with 12 mg of potassium para-aminobenzoate daily. Sixty-five patients (Group 2) ...

OBJECTIVES Evaluate the demographic data, etiology, operative findings and results of surgical treatment of penile fracture (PF) in men who have sex with men(MSM) with emphasis on sexual complications. MATERIALS AND METHODS We studied 216 patients underwent surgical correction of PF at our hospital. Patients self-identified as MSM were followed for at least 6 months. Demographic data, present...