Based on a case report in which wear of the polyethylene liner in an uncemented hip prosthesis led to the development of an intrapelvic mass, the pathogenesis, diagnosis and treatment are described. Characteristic osseous and soft tissue reactions caused by release of polyethylene particles to periarticular tissue are discussed as well as the differential diagnosis with infectious and malignant...

Two cases are presented of patients with a history of metastatic rectal adenocarcinoma presenting with a painful joint effusion. Both cases are potential examples of metastasis to periarticular bone with local infiltration to the synovium, which is one proposed mechanism of intrasynovial metastasis. While skeletal metastases are a relatively common occurrence in metastatic adenocarcinoma, intra...

Inflammatory arthritides are commonly characterized by localized and generalized bone loss. Localized bone loss in the form of joint erosions and periarticular osteopenia is a hallmark of rheumatoid arthritis, the prototype of inflammatory arthritis. Recent studies have highlighted the importance of receptor activator of nuclear factor-kappa B ligand (RANKL)-dependent osteoclast activation by i...

We describe a case of a small intra-articular foreign body in the foot presenting 48 hours following injury, which at operation showed early evidence of septic arthritis. It is essential to accurately localise periarticular foreign bodies in the foot and proceed to arthrotomy and debridement in all cases where there is radiological or clinical evidence to suggest intra-articular retention of a ...

Gout is a disease characterized by acute episodes of pain, which occurs as the result of monosodic urate crystal deposit in the joint and periarticular tissue. In some cases, gout behaves as a severe inflammatory arthopathy that is difficult to manage, generating structural joint damage and functional impairment. We report the case of a 44 years old man with gouty arthritis for 12 years, not re...

Osteoarthrosis is described in a wild, 14-year-old coyote (Canis latrans) x dog (C. familiaris) hybrid shot in southeastern Nebraska. There was ankylosis of five vertebrae, the head of the left femur was absent, and periarticular osteophytes occurred throughout the skeleton. The age is significant because wild coyotes seldom live beyond 6 years and coyote x dog hybrids are considered to be less...

If left untreated, gout may result in radiographic abnormalities, that is, cartilage loss and periarticular osteopenia plus more-or-less gout-specific radiographic abnormalities: spurs, sclerosis, and periostal new bone formation. In the current issue, Dalbeth and colleagues describe findings from about 800 joints in 20 mostly tophaceous patients, which can help clinicians to identify osteopath...

Periarticular osteolysis is a debilitating complication of inflammatory arthritis. While controversy exists as to whether pannus, itself, is capable of degrading bone, the osteoclast is clearly the principal, if not exclusive, bone resorptive cell in rheumatoid disease and other osteopenic disorders. Thus, the treatment of inflammatory osteolysis depends upon understanding the means by which th...

Osteoarthritis (OA) represents failure of the diarthrodial (synovial) joint. Although the pathologic hallmark of OA is the progressive lost of articular cartilage over the habitually loaded areas of the joint surface, OA is not a disease of only tissue cartilage, it affects all of the tissues of the joint, including the synovium, subchondral bone, capsule, ligaments, periarticular muscles and t...

Quantification of periarticular demineralization in rheumatoid arthritis by digital X-ray radiogrammetry (DXR) and peripheral quantitative computed tomography (pQCT) D.M. Renz, A. Pfeil, A. Hansch, G. Wolf , J. Böttcher Charité University Medicine Berlin, Department of Radiology, Berlin, Germany Friedrich-Schiller-University Jena, Department of Internal Medicine III, Jena, Germany Friedrich-Sch...