In this study, the relationship among four species of Polygonum (including P. hyrcanicum (three samples), P. persicaria, P. avicular, and P. hydropiper) was investigated by GC profiling. Furthermore, the major compounds of the ethylic ether extract of P. hyrcanicum were identified by GC/MS as: -bisabolol (17.5%), cedrol (15.9%), sesquisabinene hydrate (13.0%), -elemol (10.5%) and trans-longipin...

Isoprenoids are a large and diverse group of metabolites with interesting properties such as flavour, fragrance and therapeutic properties. They are produced via two pathways, the mevalonate pathway or the 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway. While plants are the richest source of isoprenoids, they are not the most efficient producers. Escherichia coli and yeasts have been extensi...

Plant δ13C-temperature (δ-T) relation has been established in many systems and is often used as paleotemperature transfer function. However, it is still unclear about the exact contributions of temperature variation to plant 13C discrimination because of covariation between temperature and precipitation (aridity), which reduces confidence in reconstruction of paleoclimate. In this study, we mea...

Research into the evasion of drug resistance and adverse effects is highly significant and urgent in the clinic. Therefore, accumulating studies have focused on the development of novel target-specific molecules related to drug resistance, and the establishment of rational therapeutic approaches. Currently, studies have shown that NF-κB activation may play an essential role in the development o...

Tlie current issue of Pain Research & Management contains an authoritative review of the efficacy of specific nonpharmacological interventions for acute procedural pain in children up to three years of age (1) (pages 321 -330), which is an abridged version of a more exhaustive review (2). These publications provide strong justification for health care professionals and parents, as well as other...

has been approved by the Examining Committee for the thesis requirement for the Doctor of Philosophy degree in Psychological and Quantitative Foundations (Educational Measurement and Statistics) at the August 2014 graduation. ii ACKNOWLEDGMENTS Looking back, once again I realize that I am surrounded by some great people, the people that I love and trust. The whole process of writing this disser...

BACKGROUND Socioeconomic mortality differentials are known to exist almost universally. Many studies show a trend towards convergence with increasing age. Information about the highest ages is very rare, though. OBJECTIVE We want to find out whether socioeconomic factors determine the chance of death in the United States among the oldest people. METHODS Based on official death count records, we...

BACKGROUND Sesquiterpenes are 15-carbon terpenes synthesized by sesquiterpene synthases using farnesyl diphosphate (FPP) as a substrate. Recently, a sesquiterpene synthase gene that encodes a 65 kDa protein was isolated from the aromatic plant Persicaria minor. Here, we report the expression, purification and characterization of recombinant P. minor sesquiterpene synthase protein (PmSTS). Insig...

BACKGROUND Persicaria hydropiper (Linn.) Delarbre is a common plant of Polygonaceae family commonly called Bishkatali in Bangladesh. Leaves of the plant are traditionally used in the treatment of rheumatic pain, gout, and skin diseases such as ringworms, scabies, boils, abscesses, carbuncles, bites of snakes, dogs or insects. This study evaluated the antinociceptive effect of the methanol extra...

In traditional Chinese medicine, Persicaria chinensis L. has been prescribed to cure numerous inflammatory disorders. We previously analyzed the bioactivity of the methanol extract of this plant (Pc-ME) against LPS-induced NO and PGE2 in RAW264.7 macrophages and found that it prevented HCl/EtOH-induced gastric ulcers in mice. The purpose of the current study was to explore the molecular mechani...