A simple, swift with good sensitivity and reproducibility, HPLC-RI method has been developed for the quantification of lactulose and related compounds (fructose, galactose, epilactose and lactose) in oral suspension formulation. The analysis was carried out by using mobile phase (water and acetonitrile 75:25) at the flow rate of 1.0 ml/min. on isocratic HPLC-RI system. After manipulating mobile...

The simultaneous estimation of Atorvastatin Calcium (ATS) and Olmesartan Medoxomil (OLM) in bulk pharmaceutical dosage forms, a new, quick, cost-effective Reverse Phase High Performance Liquid Chromatography (RP-HPLC) method has been developed. experimental design was used to achieve multivariate optimization the RP-HPLC conditions. Three independent variables were create mathematical models: A...

the present study describes a simple, accurate, precise and cost effective uv-vis spectroscopic and rp-hplc method for the estimation of ibandronate sodium (ibn). the determination of ibandronate sodium (ibn) was performed by both uv and rp-hplc method using 215 nm as the determination wavelength. the drug was dissolved in naoh solution (0.1n naoh) for estimation in uv and in distilled water fo...

A simple, sensitive and selective method of high-performance liquid chromatography (HPLC) has been successfully developed for separation of bavachinin enantiomers in Fructus Psoraleae and rat plasma. The separation and detection conditions of HPLC were optimized. Chiral bavachinin were separated with the mobile phase of methanol and water (70:30, v/v) at a flow rate of 1.0 mL/min. The linear ra...

The high mobility group (HMG) of nonhistone proteins have been investigated using two high performance liquid chromatographic techniques (HPLC). Reversed-phase HPLC under conditions of 50 mM triethylamine adjusted to pH 2.2 with phosphoric acid (solvent A) and 95% acetonitrile in water (solvent B) was used to separate proteins primarily on the basis of differences in the overall hydrophobi...

there are various methods for the analysis of potassium sorbate and sodium benzoate in food products, but a rapid and reliable method for identification of these preservatives in doogh (an iranian traditional dairy drink) is a procedure, in which high performance liquid chromatography (hplc) utilized and followed by uv diode array detection of the two preservatives. the aim of this case study w...

Zataria multiflora Boiss is used in traditional folk remedies as antiseptic, analgesic, carminative, anthelmintic medication. The main components of Z. multiflora are phenolic compounds such as thymol and carvacrol. The aim of this study was developed a simple and rapid method for determination of the thymol in different extracts of Z. multiflora by HPLC method. The dried aerial parts of Z. mul...