objective: the present study aimed to compare the effectiveness of metacognitive therapy (mct) and cognitive-behavior therapy (cbt) in treating iranian patients with major depressive disorder (mdd). methods: thirty three outpatients meeting dsm-iv-tr criteria for mdd without any other axis i and ii disorders were randomly assigned to one of three treatment conditions, i.e. mct, cbt and pharmaco...

zno nanorods and nanoparticles have been easily prepared via the decomposition of two simple schiff base zinc (ii) complexes, namely (n,n'–disalicylalethylenediamine)zince(ii) and (n,n'–disalicylalphenylenediamine)zince(ii) under microwave irradiation. the decomposition products of the complexes were characterized by ft-ir, xrd, sem, edx and uv-visible spectroscopy.  ft-ir, xrd and edx results ...

                The value of frost tolerance in wheat is increased with decreasing the temperature in late autumn and/or early winter (phase I, acclimation), then shows plateau state for a period with the coldest temperature (II), finally appears to decrease with warming the temperature (III, de-acclimation). This study was aimed to determine the threshold frost hardiness in wheat for avoiding ...

The standard phase II trial design has changed dramatically over the past decade. Randomized phase II studies have essentially become the standard phase II design in oncology for a variety of reasons. The use of these designs is motivated by concerns about the use of historical data to determine if a new agent or regimen shows promise of activity. However, randomized phase II designs come with ...

The traditional oncology drug development paradigm of single arm phase II studies followed by a randomized phase III study has limitations for modern oncology drug development. Interpretation of single arm phase II study results is difficult when a new drug is used in combination with other agents or when progression-free survival is used as the endpoint rather than tumor shrinkage. Randomized ...

In some applications of statistical process monitoring, a quality characteristic can be characterized by linear regression relationships between several response variables and one explanatory variable, which is referred to as a “multivariate simple linear profile.” It is usually assumed that the process parameters are known in Phase II. However, in most applications, this assumption is viola...