The aim of this study was to estimate pubertal age and to assess the level of physical development of preterm girls with defective vision. The study material – anthropometric data (body height and weight, BMI) and information on the age of menarche were collected from 155 subjects with defective vision (partially sighted and blind). Median age at menarche was estimated by probit analysis. The g...

Objective To characterize the physical frailty phenotype and its associated physical and functional impairments in mild cognitive impairment (MCI). Method Participants with MCI (N = 119), normal low cognition (NLC, N = 138), and normal high cognition (NHC, N = 1,681) in the Singapore Longitudinal Ageing Studies (SLAS-2) were compared on the prevalence of physical frailty, low lean body mass, ...

OBJECTIVES While cognitive impairment is frequently reported in HIV-positive individuals and has historically been associated with poorer functional outcomes, the associations between cognitive impairment and patient-reported outcome measures (PROMs) in contemporary cohorts are unclear. METHODS We tested cognitive function using a computerized battery (CogState™ ) in 290 HIV-positive and 97 H...

Introduction: Cognitive impairment that affects older adults is commonly associated with an inflammatory imbalance, resulting in decreased physical fitness. Exercise has been pointed to mitigate immunosenescence and cognitive impairment associated with aging, while increase in physical fitness. However, few studies explored the relationship between changes in cytokine concentration and improvem...

OBJECTIVE To investigate by a cross sectional study in patients with rheumatoid arthritis (RA) the relationship between measures of impairment, activity limitation, and participation of the model of functioning and disability (ICIDH-2). METHODS Inclusion data of patients with RA (n=803) from the Swiss Clinical Quality Management Group were used. Impairments were measured by the Short Form-36 ...

Fear-avoidance beliefs have been identified as an important psychosocial variable in patients with chronic disability doe to low back pain. The importance of fear-avoidance beliefs for individuals with acute low back pain has not been explored. Seventy-eight subjects with workrelated low back pain of less than 3 weeks’duration were studied. Measurements of pain intensity, physical impairment, d...

BACKGROUND AND PURPOSE We sought to determine whether there are racial differences in physical and functional impairments resulting from an initial ischemic stroke. METHODS We conducted a prospective, county-wide, multisite cohort study including a university hospital, a community hospital, and a Veterans Affairs hospital. The study population was an inception cohort of 145 patients hospitali...

BACKGROUND AND PURPOSE Handicap, although more relevant to the patient than impairment or disability, has received little attention in people with stroke. The aim of this study was to identify, in an unselected population, factors determining handicap at 2 years after stroke. METHODS All first-ever cases of stroke in a population of 306 631 over a 1-year period were assessed. Stroke severity,...

Cognitive impairment in multiple sclerosis is an increasingly recognized entity. This article reviews the cognitive impairment of multiple sclerosis, its prevalence, its relationship to different types of multiple sclerosis, and its contribution to long-term functional prognosis. The discussion also focuses on the key elements of cognitive dysfunction in multiple sclerosis which distinguish it ...