OBJECTIVE — Mutations in the highly homologous transcription factors hepatocyte nuclear factor (HNF)-1 and -1 cause maturity-onset diabetes of the young types 3 and 5, respectively. Diabetes due to HNF-1 mutations is well characterized. However, physiological assessment of the HNF-1 phenotype is limited. We aimed to test the hypothesis that the diabetes phenotype due to HNF-1 mutations is simil...

Among all the –omics approaches, proteomics and metabolomics have received increased attention over last decade. Both approaches reached a certain level of maturity, showing their relevance in numerous clinical applications, including biomarkers discovery, improved diagnosis, staging, prognosis diseases, as well better knowledge on various (patho-)physiological processes. Analytically, reversed...

Previously recognized color and pattern variants of adult Cichla temensis in Amazon flood pulse river environments reflect the cycling of individuals through seasonal sexual maturity and spawning. Individuals also vary in shape from blocky to fusiform. To determine if shape differences are related to patterns of fat reserve deposition and utilization, and to quantify the relationship of shape w...

objective: electroencephalogram is a reliable reflection of many physiological factors modulating the brain. the bispectrum is very useful for analyzing non-gaussian signals such as eeg, and detecting the quadratic phase coupling between distinct frequency components in eeg signals.the main aim of this study was to test the existence of nonlinear phase coupling within the eeg signals in a certa...

due to its wide adaptability, chickpea is considered as an important crop in arid, semi-arid and in marginal lands. most important factors which limit yield of chickpea are short length of physiological growth period and susceptibility to cold and diseases, especially ascochyta rabie. releasing a chickpea cultivar with high yield and good characteristics such as cold tolerance, resistance to di...

Munida subrugosawas sampled monthly from November 1997 to November 1999 in the Beagle Channel by means of an epibenthic trawl. The reproductive cycle started in May, re£ected by the occurrence of ovigerous females. Maximum size of oocytes, maximum value of gonadosomatic index in females (16.8 gmmcarapace length [CL]71) and males (1.6 gmmCL71), and the proportion ( 70%) of ovigerous females with...

Experiments were carried out to investigate the physiological (dry weight of root, stem, peg, flowers plant, fruits sets percent, pod yield (kg plot), 100-kernel weight, days to flowering and maturity) and biochemical (endogenous proline level) traits of groundnut cultivar Swat Phalli-96 under drought stress. The result showed that drought stress significantly (p < 0.05) reduced dry weight of r...

The sequential morphologic changes of rabbit duodenal mucosa-submucosa were studied from primodial stage to birth in 15 fetuses and during the early days of life in 21 rabbit newborns till maturity using light, scanning and transmission electron microscopy. Fetal rabbit duodenum develops from a simple tube of stratified epithelium to a tube containing villus and intervillus regions of simple co...