Introduction: La péritonite infectieuse (PI) est une des complications les plus sévères et les plus fréquentes de la dialyse péritonéale (DP). But : Déterminer le taux des PI et les germes en causes, et évaluer l’efficacité des protocoles thérapeutiques entrepris chez les patients traités par DP au CHU de Rabat. Méthodes: Etude rétrospective effectuée en Septembre 2009 chez tous les patients tr...

The ultrastructures of the pituitary pars intermedia of 11 male sheep about 1-13 months of age were observed. The following cells were distinguished in the sheep pars intermedia: pars intermedia glandular cells, marginal cells, interstitial cells, follicular cells, pars distalis-like granular cells, degenerating cells and mast cells. The pars intermedia glandular cells contain a well-developed ...

Activating mutations in the fibroblast growth factor 23 (FGF23) gene were identified as the cause of autosomal dominant hypophosphataemic rickets (ADHR) [1]. This secreted protein was later shown to play a role in both physiological and pathological phosphate handling. FGF23 may be the key pathogenetic molecule in three different diseases with hypophosphataemia and inappropriate regulation of v...

BACKGROUND AND PURPOSE To examine the neurophysiological basis for the pronounced differences in hyperactivity and impulsiveness that distinguish the predominantly inattentive type of attention-deficit/hyperactivity disorder (ADHD-PI) from the combined type of the disorder (ADHD-C). METHODS Event-related brain responses to a go/no-go test of inhibitory control were measured with functional ma...

OBJECTIVE The aim of this study is to prospectively compare the accuracies of transcranial color-coded sonography (TCCS) and transcranial Doppler (TCD) in the diagnosis of elevated intracranial pressure. METHODS A prospective, blinded, head-to-head comparison of TCD and TCCS methods using intracranial pressure (ICP) measured continuously via an intraparenchymal catheter as the reference stand...

BACKGROUND In congestive heart failure (CHF), the prognostic significance of impaired respiratory muscle strength has not been established. METHODS AND RESULTS Maximal inspiratory pressure (Pi(max)) was prospectively determined in 244 consecutive patients (207 men) with CHF (ischemic, n=75; idiopathic dilated cardiomyopathy, n=169; age, 54+/-11 years; left ventricular ejection fraction [LVEF]...

The extracellular pH (pi I,.) in many solid tumors is often lower than in normal tissues. Cells may survive conditions of acid pi 1, because antiports in their membrane exchange Na* for 11+,or 11CX)., for Cl~, and thus regulate the intracellular pH (pH,). We have therefore assessed the effects of drugs which interfere with regulation of pi I; on survival of Chinese hamster ovary and human bladd...

We studied with biochemical and immunofluorescent techniques the interactions between the actin microfilament and tubulin microtubule cytoskeleton and Na+/P1 co-transport in opossum kidney cells, a line with proximal tubular characteristics. On brief (5 min) incubation of the cells with a low (0.1 mM) concentration of Pi, a rapid F-actin depolymerization takes place, which fails to occur in cel...

BACKGROUND It is unknown whether HIV-positive patients experiencing virologic failure (VF) on boosted-PI (PI/r) regimens without drug resistant mutations (DRM) by standard genotyping harbor low-level PI resistant variants. CASTLE compared the efficacy of atazanavir/ritonavir (ATV/r) with lopinavir/ritonavir (LPV/r), each in combination with TVD in ARV-naïve subjects. OBJECTIVE To determine if...