BACKGROUND A previous study had identified 45 items assessing the impact of atopic dermatitis (AD) on the whole family. From these it was intended to develop two separate scales, one assessing impact on carers and the other determining the effect on the child. METHODS The 45 items were included in three clinical trials designed to test the efficacy of a new topical treatment (pimecrolimus, El...

Correspondence to: S Conroy, The Medical School, Derbyshire Children’s Hospital, Uttoxeter Road, Derby DE22 3DT, UK; Sharon.conroy@ nottingham.ac.uk _________________________ E czema is the most common chronic skin disease, affecting 15 to 20% children in developed countries. Altered T cell function appears to be the primary immunological abnormality and patients have raised levels of IgE. Most...

PROBLEMA: la dermatitis atópica (DA) es condición dermatológica pediátrica más común. Considerada una enfermedad inflamatoria crónica, caracterizada por prurito intenso, su tratamiento requiere del uso de terapia activa para controlar los brotes y profiláctica el mantenimiento integridad barrera cutánea. OBJETIVO: describir abordaje terapéutico en pediatría dupilumab manejo DA moderada a grave....

Fox-Fordyce Disease (FFD) is a rare, chronic, pruritic, inflammatory disorder of apocrine glands. It is characterized by dome-shaped, firm, discrete, skin-colored, and monomorphic perifollicular papules. The most common sites of involvement are axillae and anogenital and periareolar regions which are rich in apocrine sweat glands. Treatment is difficult. Topical, intralesional steroids, topical...

A 75-year-old Hispanic woman with no significant past medical historywas referred to uswith a 2-month history of very itchy dermatitis involving the eyelids, chin, and the anterior part of the ears. Clinical features suggested an airborne contact dermatitis. However, patch testing with the North American baseline series gave negative results. Further patch tests with fragrances and cosmetic and...

Lichen sclerosus is a chronic relapsing disease, usually treated with ultra-potent corticosteroids. As immunological alterations are considered important aetiopathogenetic factors in lichen sclerosus, the new immunomodulating topical agents, such as tacrolimus and pimecrolimus, have been employed sporadically as alternative therapies. The aim of this study was to evaluate the therapeutic effect...