نتایج جستجو برای: piperazin derivative
تعداد نتایج: 64343 فیلتر نتایج به سال:
a mixture of acetaminophen, diphenhydramine hydrochloride and pseudoephedrine hydrochloride is used for the symptomatic treatment of common cold. in this study, a derivative spectrophotometric method based on zero-crossing technique was proposed for simultaneous determination of acetaminophen, diphenhydramine hydrochloride and pseudoephedrine hydrochloride. determination of these drugs was perf...
We develop a non-anticipative calculus for functionals of a continuous semimartingale, using an extension of the Ito formula to path-dependent functionals which possess certain directional derivatives. The construction is based on a pathwise derivative, introduced by B Dupire, for functionals on the space of right-continuous functions with left limits. We show that this functional derivative ad...
Lurasidone [(3aR,4S,7R,7aS)-2-[(1R,2R)-2-[4-(1,2-benzisothiazol-3-yl)piperazin-1-ylmethyl]cyclohexylmethyl]hexahydro-4,7-methano-2H-isoindole-1,3-dione hydrochloride; SM-13496] is an azapirone derivative and a novel antipsychotic candidate. The objective of the current studies was to investigate the in vitro and in vivo pharmacological properties of lurasidone. Receptor binding affinities of lu...
246 Introduction: 469 Discussion: 1447 References: 24 Tables: 6 Figures: 11 Abbreviations: DPP-IV, dipeptidyl peptidase IV; GLP-1 glucogen-like peptide 1; PF-00734200, 3,3-Difluoropyrrolidin-1-yl)((2S,4S)-4-(4-(pyrimidin-2-yl)piperazin-1-yl)pyrrolidin-2yl)methanone, ESI, electrospray ionization; HFAA, hexaflouroacetylacetone; SD, Sprague Dawley; GLP-1, glucagon like peptide; FAP, fibroblast act...
The title mol-ecular salts, C10H15N2 (+)·C6H6ClN2O2 (-), (I), and C10H15N2 (+)·C7H8ClN2O2 (-), (II), consist of 4-phenyl-piperazin-1-ium cations with a 6-chloro-5-ethyl-2,4-dioxopyrimidin-1-ide anion in (I) and a 6-chloro-5-isopropyl-2,4-dioxopyrimidin-1-ide anion in (II). Salt (I) crystallizes with two independent cations and anions in the asymmetric unit. In the crystal structures of both sal...
Vilazodone HCl (VLN) is chemically 5-(4-[4-(5-cyano-1Hindol-3-yl) butyl] piperazin-1-yl) benzofuran-2-carboxamide hydrochloride [1] (Figure 1). It contains an indole piperazine that utilizes its function as an SSRI and 5-HT1a receptor partial agonist [2]. It belongs to the category of serotonergic antidepressant approved by FDA (Food and Drug Administration) for treatment of depressive disorder...
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