During anti-Malassezia screening of plants by CLSI broth microdilution method, Cladia aggregata (Swartz) Nyl. (family Cladoniaceae), a fruticose lichen from Sikkim (northeast Himalayan region), has been found effective at minimum inhibitory concentrations (mg/mL) of 2.72, 0.63, and 1.28 against yeast-like fungi namely, M. furfur, M. globosa and M. sympodialis, respectively. These test pathogens...

Pityriasis alba is a common hypomelanosis which is generally seen in young children. There is no specific known cause for this condition; however, studies to elucidate pathogenic factors seem to suggest that there are at least five separate causes for the condition. This list includes dermatitis, photosensitivity, fungal and bacterial pathogenesis, and post-inflammatory alterations. An evaluati...

Progressive macular hypomelanosis is an acquired skin pigmentation disorder that was initially thought to be related to racial characteristics, but is currently more often associated with the presence of Propionibacterium acnes. A 23-year-old woman was seen for the progressive appearance over a 5-year period of asymptomatic whitish lesions on the trunk (Figures 1A and 2). The lesions were poorl...

Epidermodysplasia verruciformis (EV) is a rare auto­ somal recessive disease characterised by abnormal susceptibility to disease-specific human papillomaviruses (HPVs), possibly due to suppressed cellular innate im­ munity. EVER1/TMC6 or EVER2/TMC8 gene mutations are often found in EV (1). All patients with EV usually have similar skin lesions from their childhood, involving disseminated flat w...

Epidermodysplasia verruciformis (EV) is a rare genodermatosis, first described by Lewandosky and Lutz in 1922.1 This premalignant lesion has occurred de novo, as well as in patients with impaired cell-mediated immunity, including those infected with HIV, systemic lupus erythematosus2 (SLE), or lymphoma,3 or those who have received a solid organ transplant.4 In immunocompromised and immunocompet...