BACKGROUND Carotid plaque MRI has been a useful method to characterize vulnerable atherosclerotic plaque elements. Recent investigations have suggested that source images from CT angiography (CTA) and MR angiography (MRA) can identify the simple high-risk features of symptom-producing carotid artery plaque. We studied the correlation and relative diagnostic accuracies of CTA and MRA source imag...

PURPOSE This study compared the small head Oralgiene 60 Second Time Machine powered toothbrush, used for 60 seconds, with the Braun Oral-B Mickey Mouse powered toothbrush and a manual toothbrush (Oral-B Rugrats 20), each used for 2 minutes, for efficacy in plaque removal and reduction of gingival inflammation in young children. METHODS Fifty-eight children, ages 4 to 5 years old, were randoml...

OBJECTIVE To determine the relation between presence of H. pylori in supra-gingival dental plaque with oral hygiene habits and oral health status of patients suffering from symptomatic dyspepsia. STUDY DESIGN Descriptive study. PLACE AND DURATION OF STUDY The Department of Oral Health Sciences, Shaikh Zayed FPGMI, Lahore, from September 2008 to August 2009. METHODOLOGY One hundred and fif...

We use a computational model to explore the effect of foam cell accumulation on plaque regression following an increase in high density lipoprotein (HDL) influx into the plaque. Atherosclerotic plaque formation is the outcome of cellular and cytokine responses to low density lipoproteins (LDL) that penetrate the artery wall following an injury to the endothelium and become modified. We modelled...

The current study describes the incidence and phenotype of plaque rupture complications in murine vein grafts. Since matrix metalloproteinases (MMPs) are highly involved in atherosclerotic plaque vulnerability and plaque rupture, we hypothesized that this model can be validated by overexpression of the MMP inhibitor TIMP-1. First we studied 47 vein grafts in hypercholesterolemic ApoE3*Leiden mi...

AIM To compare the safety and efficacy of two manual toothbrushes, Oral-B Exceed and Asian Colgate 360 masculine, in removing plaque. METHODS AND MATERIALS The study used an examiner-blind, two-treatment, randomized, four-period (visits) crossover design. At the first visit, subjects received a baseline plaque examination; plaque was scored using the Rustogi et al. Modified Navy Plaque Index ...

BACKGROUND AND PURPOSE Recent studies indicate that the urokinase system could have an important role in atherogenesis and plaque rupture. The relationships among the soluble urokinase plasminogen activator receptor (suPAR), carotid plaque, and incidence of ischemic stroke and coronary artery disease (CAD) events were studied in a prospective cohort. METHODS Occurrence of carotid plaque and p...

BACKGROUND Fermentable carbohydrates and microorganisms in the plaque play a significant role in the pathogenesis of dental caries. Oral clearance of sugars and salivary pH is affected by the presence of plaque. AIMS AND OBJECTIVES This study was conducted to study the effect of the presence of plaque on the salivary clearance of sucrose and on salivary pH. MATERIALS AND METHODS The study d...

BACKGROUND AND PURPOSE Ultrasound of carotid arteries provides measures of intima media thickness (IMT) and plaque, both widely used as surrogate measures of cardiovascular disease. Although IMT and plaques are highly intercorrelated, the relationship between carotid plaque and IMT and cardiovascular disease has been conflicting. In this prospective, population-based study, we measured carotid ...

Previous studies have demonstrated that the hydrolysis of the trypsin substrate N-benzoyl-DL-arginine-2-naphthylamide (BANA), by subgingival plaque obtained from a single site, correlates best with the numbers and proportions of spirochetes in plaque samples and may serve as an indicator of clinical disease. In this investigation, we determined whether the association between BANA hydrolysis an...