Abstract Background Cardiovascular heart disease is the leading cause of mortality worldwide, with rupture or thrombosis an atherosclerotic plaque being main reason behind acute coronary syndrome. It has already been established that morphology plaques determine their stability. A lipid rich lesion a thin fibrous cap more prone to compared solid lesions. In PROSPECTII study we used Near infrare...

Boston and ABC strains of mumps virus produced plaques approximately 1.0 mm in diameter in monolayers of BGM cells. The plaques were circular and either clear or target-like in form. Ricki strain virus produced plaques of similar size and form but, in addition, a red plaque was observed with this agent. The vaccine strain of mumps virus, Jeryl Lynn, produced minute clear plaques approximately 0...

Inflammation plays a major role in all phases of atherosclerosis. Stable plaques are characterized by a chronic inflammatory infiltrate, whereas vulnerable and ruptured plaques are characterized by an "active" inflammation involved in the thinning of the fibrous cap, predisposing the plaque to rupture. Although a single vulnerable atherosclerotic plaque rupture may cause the event, there are ma...

Plaque production by 55 rhinoviruses in several lines of HeLa cells is reported. Forty-nine types produced macroscopic plaques under the conditions described previously employing 30 mM MgCl(2) and 30 mug/ml of DEAE-dextran in overlay and M HeLa cells. Basically three kinds of plaques were observed: clear large and intermediate sized plaques and small turbid plaques. Five rhinoviruses produced p...

"Vulnerable" plaques are atherosclerotic plaques that have a high likelihood to cause thrombotic complications, such as myocardial infarction or stroke. Plaques that tend to progress rapidly are also considered to be vulnerable. Besides luminal stenosis, plaque composition and morphology are key determinants of the likelihood that a plaque will cause cardiovascular events. Noninvasive magnetic ...

Magnetic resonance imaging (MRI) has been shown to be far more sensitive than computed tomography (CT) in the detection of multiple sclerosis plaques within the brain. Unlike CT, MRI is also able to detect multiple sclerosis in the brainstem and cerebellum. This report is the first description of MRI of multiple sclerosis plaques within the cervical spinal cord. Twenty-one patients with clinica...

Granuloma faciale (GF) is a rare cutaneous disorder categorized as a localized form of small-vessel vasculitis. Clinically, it manifests as single or multiple well-demarcated red-brown plaques, papules and nodules, nearly always confined to the face. Herein, we report a 39-year-old man with multiple red-brown infiltrated plaques on face and extrafacial lesions on back, shoulders and both arms. ...

Nous rapportons le cas d'une femme âgée de 75 ans, hypertendue sous traitement, pseudophake au niveau de l'œil droit, cataracte de l'œil gauche et chez qui l'examen ophtalmologique décèle de façon bilatérale et symétrique des zones de dépression sclérale de couleur grisâtre située en avant de l'insertion des deux muscles droits internes. La plaque sclérale est le résultat d'une dégénérescence d...