objective(s) bone is a dynamic tissue that is continuously renewed throughout life by the process of bone remodeling. antioxidant system might be involved in the pathogenesis of bone loss, so the aim of this study was to evaluate the total antioxidant capacity (tac), vitamin c and vitamin e levels of plasma besides measuring enzymatic antioxidants, superoxide dismutase (sod), catalase (cat) and...

in this study, the pharmacokinetic parameters of two marketed tablet formulations of ketoconazole were studied, and the relative bioavailability of the test formulation was compared with a reference formulation. a single dose (12x2) double blind randomized cross-over study of a generic formulation of ketoconazole tablet (2x200 mg), and a commercial brand, nizoral tablet (2x200 mg, janssen pharm...

background: considering the increasing incidence of coronary artery stenosis and its related complications, the importance of its etiology and inconsistent reports we aimed to determine the relationship between oxysterol, serum levels and severity of coronary atherosclerosis and effect of statins on oxysterol.  methods: a total of 85 patients referred to taleghani hospital, tehran, iran during ...

dietary antioxidants including phenolic compounds are believed to be effective nutrients in the prevention of oxidative stress related disease. pomegranate has been used for centuries in ancient cultures for its medicinal purpose and is widely acknowledged for antioxidant properties. the present study was designed to assess the effect of pomegranate fresh fruit consumption on the plasma antioxi...

background: in this study we have prepared the iga solution from normal human plasma using plasma fractionation and ion exchange chromatography. materials and methods: using fractionation of plasma with cold ethanol (starting with 8% ethanol), fraction iii was prepared as a suitable source for iga preparation. then it was treated with caprylic acid for separation of impurities. for enrichment o...

background ghrelin and obestatin are orexigenic and anorexigenic peptides, respectively. it appears that an accurate balance between theses peptides is important for regulating energy homeostasis and body weight. objectives the aim of this study was to identify the possible mechanisms by which circuit resistance training influences energy homeostasis and weight control. patients and methods twe...

patients with limbic encephalitis usually present with new onset mesial temporal lobe seizures, progressive memory disturbance, and a variety of other behavioral, emotional, and cognitive changes. autoimmune inflammation of the limbic gray matter structures of the human brain has recently been identified as major cause of mesial temporal lobe epilepsy with interictal temporal epileptiform activ...

conclusions the high prevalence of fungaemia and mortality could be attributed to many patients on chronic immunosuppressive therapy. nonetheless, cpfa albeit expensive, does add to our armamentarium of extracorporeal treatment for severe sepsis. regional citrate anticoagulation with cpfa may overcome problems with filter clotting. objectives the main objective was to review our centers' e...