Autism is a severe developmental disorder whose neurological basis is largely unknown. The aim of this study was to identify the shape differences of the corpus callosum between patients with autism and control subjects. Anatomical landmarks were collected from midsagittal magnetic resonance images of 25 patients and 18 controls. Euclidean distance matrix analysis and thin-plate spline analyses...

The role of the cranial base in the emergence of Class III malocclusion is not fully understood. This study determines deformations that contribute to a Class III cranial base morphology, employing thin-plate spline analysis on lateral cephalographs. A total of 73 children of European-American descent aged between 5 and 11 years of age with Class III malocclusion were compared with an equivalen...

Morphometrics, a new branch of statistics, combines tools from geometry, computer graphics and biometrics in techniques for the multivariate analysis of biological shape variation. Although medical image analysts typically prefer to represent scenes by way of curving outlines or surfaces, the most recent developments in this associated statistical methodology have emphasized the domain of landm...

Craniofacial registration is used to establish the point-to-point correspondence in a unified coordinate system among human craniofacial models. It is the foundation of craniofacial reconstruction and other craniofacial statistical analysis research. In this paper, a non-rigid 3D craniofacial registration method using thin-plate spline transform and cylindrical surface projection is proposed. F...

This work considers tracking of deforming soft tissues in sequences of three-dimensional ultrasound images. The chosen approach to the tracking is basedon modeling the deformations using the thin-plate spline warp. In practice, thetracking is reduced to the estimation of the changes in control point locations byexamining the intensity changes of neighbouring three-dimensional im...

Nonrigid registration of 3D tomographic images of di erent modalities (e.g., CT and MR images) is a key issue for neurosurgery and radiotherapy planning. Here, we consider image registration based on a set of corresponding anatomical point landmarks and approximating thin-plate splines. With this approach it is possible to take into account landmark localization errors and thus to control the i...

vVe discuss procedures based on non parametric regression for estimating the dominant Lyapunov exponent Al from time-series data generated by a system xt =f(xt _l' x t _2' ... xt_d)+o-et , where XtEIR, and {et } is an iid sequence of random variables. For systems with bounded fluctuations in x t ' '\1 >0 is the defining feature of chaos. vVe show that any consistent estimator of the partial of/...