Different types of platelets in various types of plasma were subjected to levels of shear stress that produce irreversible platelet aggregation in normal platelet-rich plasma (PRP). At shear stresses of 90 or 180 dyne/cm2 applied for 30 seconds or five minutes, aggregation was either absent or only transient and reversible using severe von Willebrand's disease (vWD) PRP (less than 1% von Willeb...

Objective To compare the efficacy of intradermal platelet-rich-plasma vs. tranexamic acid in treatment melasma. Study design Non-randomised controlled trial. Place and duration study Sheikh Zayed Hospital, Rahim Yar Khan from 1st October 2019 to 30th April 2020. Methodology Cases melasma either gender with age 20-40 years, were included. Diagnosis was made clinically on basis hyperpigmentation ...

UNLABELLED Dental retentions have a high prevalence among the general population and their removal can involve multiple complications. The use of platelet rich plasma has been proposed in an attempt to avoid these complications, as it contains high growth factors and stimulates diverse biological functions that facilitate the healing of soft and hard tissues. OBJECTIVES To evaluate the availa...

INTRODUCTION: Platelet-rich plasma (PRP) belongs to one plasma division isolated by centrifugation of whole blood. From 1981 to 1991, a number of different growth factors containing platelets were reported one after another, such as platelet-derived growth factor (PDGF), transforming growth factor beta 1 (TGF-b1), transforming growth factor beta 2 (TGFb2), insulin-like growth factor (IGF), epid...

IMPORTANCE The promising therapeutic potential and regenerative properties of platelet-rich plasma (PRP) have rapidly led to its widespread clinical use in musculoskeletal injury and disease. Although the basic scientific rationale surrounding PRP products is compelling, the clinical application has outpaced the research. OBJECTIVE The purpose of this article is to examine the current concept...

BACKGROUND The increasing interest in platelet-rich plasma (PRP) based therapies is as yet accompanied by inconsistent information regarding nearly all aspects of handling and application. Among these storage stability of processed platelet-rich products may be the basis for a more flexible application mode. The objective of this study was (1) to estimate the storage stability of growth factors...

Skar atrofi merupakan komplikasi umum akne dan sangat memengaruhi kualitas hidup pasien. Microneedling dengan PRP untuk memperbaiki skar tergolong sederhana, aman, efektif. Teknik ini menggunakan jarum mikro menusuk kulit secara superfisial menghancurkan kolagen rusak di lapisan atas dermis, mengaktivasi kaskade penyembuhan luka normal yang menstimulasi pembentukan baru sehingga tampilan skar. ...

BACKGROUND AND OBJECTIVES The aim of this study was to compare culture-expanded, bone marrow-derived mesenchymal stem cells (MSCs) and platelet-rich plasma (PRP) loaded to biphasic calcium phosphate (BCP) bone ceramic in the repair of rat calvarial bone. MATERIALS AND METHODS Critical-size (7 mm dia.) calvarial defects were prepared in the frontal-parietal bones of 90 adult female Sprague-Daw...