flective, with a regular structure and moderate sound attenuation. This tumorwascharacteristicof pleomorphicadenomainseveralways. The patient had a painless change in appearance for at least 1 year. The lesionwasoval,wellcircumscribed,and appeared encapsulated on both computed tomographic and ultrasonographic studies. However, it showed significant,diffusecalcificationonboth imaging studies. In...

The anti-apoptotic protein Mcl-1 is highly expressed in various types of malignant tumors. Overexpression is reported to correlate with poor prognosis and disease progression. We report the expression levels of Mcl-1 in tumor samples of the parotid gland. A retrospective study containing 108 patients was performed. A tissue microarray of six malignancies of the parotid gland and pleomorphic ade...

Background and aims. Various morphologies are seen in different salivary gland tumorsor within an individual tumor, and the lesions show divers biological behaviors. Experimental results support the hypothesis that increased CrkII proto-oncogene is associated with cytokine-induced tumor initiation and progression by altering cell motility signaling pathway. The aim of this study was to assess t...

BACKGROUND Carcinosarcoma of the salivary glands is a rare neoplasm, and the minimally invasive form constitutes a subgroup with a more favorable prognosis. The cytomorphologic features of this neoplasm can be appreciated on fine-needle aspiration biopsy. METHODS AND RESULTS We present a patient with a minimally invasive carcinosarcoma ex non-recurrent pleomorphic adenoma (Ca ex PA) who under...

INTRODUCTION Slow evolution pleomorphic parotid adenoma may be diagnosed late. These giant tumors have a functional, esthetic, and social impact. They raise prognostic issues because of the risk of degeneration. We present a case of a giant pleomorphic adenoma involving the parotid glands and try to explain the reasons for the diagnostic delay and describe therapeutic specificities. CASE REPO...

BACKGROUND:. The lacrimal gland is un-capsulated, multilobulated secretory gland situated in the lacrimal gland fossa, behind the supratemporal orbital rim. Tumor and Lesion of the lacrimal gland contain 5 to 18 % of all orbital mass. Aims and objectives: To study the incidence and prevalence of tumor of lacrimal gland. To study the clinical pattern with regard to age, incidence, gender distrib...

Malignant mixed tumors of salivary gland are extremely rare tumors defined by the presence of malignant epithelial and mesenchymal components together. We report here a case of carcinosarcoma arising from a recurrent pleomorphic adenoma of submandibular salivary gland in a 36 year old woman. Histology showed a monomorphic picture dominated by malignant mesenchymal component with mixed nature pr...

BACKGROUND Salivary gland tumours, which account for approximately 3% of head-neck cancers, are a heterogeneous group and thus it is difficult to identify their epidemiological characteristics. The aim of this study is to determine demographic features and histopathologic distribution of parotid neoplasms in a large sample from Turkey. MATERIALS AND METHODS This study was conducted retrospect...

A 45-year-old female patient visited the clinic due to ear fullness. A 8 mm sized mass was found in the external auditory canal. It was surgically removed and the pathology exam confirmed epithelial-myoepithelial carcinoma (EMC). EMC is glandular epithelial neoplasm of the salivary gland. EMC originating from the external auditory canal is very rare, and only 1 case has been reported so far in ...