| This paper discusses a statistical approach to static timing analysis. Delays of gates and wires are modeled by stochastic values instead of the triple best case, typical and worst case delay. This has the advantage of avoiding the overly pessimistic (optimistic) outcome of traditional worst (best) case calculations. The paper proposes a new scheme to perform the delay calculations with stoch...

The design of logical topologies in wavelength-routing multihop optical networks is a well-studied problem. In this paper, we consider logical topology (LT) design over the popular ring and linear topologies. Our objective is the minimization of the electronic processing delay for the worst case traffic flow. For uniform traffic between nodes, this delay minimization corresponds to minimizing t...

ATM networks being a connection-oriented technology are providing service for real-time communication. Before two hosts can communicate, a connection has to be established between them. After a connection is established, messages are divided into fixed size packets called cells and are being sent from a source host to a destination host. Real-time communication service requires the underlying n...

Osteoarthritis (OA) is a low grade systemic inflammatory disease in which many inflammatory mediators are known to be elevated in the peripheric blood. Blood platelet lymphocyte ratio (PLR) and mean platelet volume (MPV) are accepted as novel markers in many of the systemic inflammatory disorders, but have not been investigated in synovitis-free radiographic OA yet.The aim of this study was to ...

PURPOSE We aimed to investigate the relationship between pretreatment neutrophil-to-lymphocyte ratio (NLR)/platelet-to-lymphocyte ratio (PLR) and the estimation of hormone-receptor-negative (HR-) breast cancer patients' survival in a Chinese cohort. PATIENTS AND METHODS Of 434 consecutive HR- nonmetastatic breast cancer patients treated between 2004 and 2010 in the Affiliated Hospital of Acad...

Background Inflammatory response markers plays an important role in tumor progression. The aim of this analysis was to evaluate whether the neutrophil-to-lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) could predict the prognosis of nasopharyngeal carcinoma(NPC). Materials and Methods 247 patients who underwent Intensity Modulated Radiation Therapy( IMRT )were enrolled from Jan...

BACKGROUND In this study we investigated the potential of neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio (PLR), mean platelet volume (MPV), and red cell width distribution (RDW) as new inflammatory markers to identify chronic inflammations during symptom-free periods in children diagnosed with Familial Mediterranean Fever (FMF). MATERIAL/METHODS The study included 153 children d...

BACKGROUND Inflammatory response markers have been proposed to predict the clinical outcomes in various cancers. The aim of this study was to explore the influence of the neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) on the prognosis of osteosarcoma. METHODS Three hundred fifty-nine patients who underwent curative surgery for osteosarcoma were enrolled from 2005 ...

In this paper, we present a systematic framework to identify delay marginalities in a design during first silicon validation. Our method guarantees the excitation of the worst-case delay of the chips in the first silicon batch without introducing any pessimism. It embodies several innovations, including a resilient gate delay model to capture process variations, new conditions that vectors must...

stract We introduce a capacity reservation scheme for multimedia trac. We compare it to other algorithms in the literature. It has been implemented and its worst-case performance has been analysed. It appears to give a noticeably improved quality of service to delay-sensitive trac.