Abstract For the in vitro examination of effects on cells and tissues metal ions derived from implants by wear corrosion, a system is needed to release controlled sustained manner. As small concentrations may have an impact biological systems, corresponding slow over defined period time necessary. Here, manufacturing method polymeric Poly(L-lactic acid) (PLLA) films with incorporated cobalt via...

Biodegradable thermogelling copolymer hydrogels have great applicative potential in areas such as sustained drug release, gene delivery and tissue engineering. These injectable materials can be implanted in the human body with minimal surgical intervention. The thermosensitive copolymers have been incorporated with a variety of biocompatible and biodegradable components such as poly(D,L-lactic ...

The grim prognosis for patients diagnosed with malignant gliomas necessitates the development of new therapeutic strategies for localized and sustained drug delivery to combat tumor drug resistance and regrowth. Here we introduce drug encapsulated aerosolized microspheres as a biodegradable, intelligent glioma therapy (DREAM BIG therapy). DREAM BIG therapy is envisioned to deliver three chemoth...

Now a day there is an emerging interest in replacing non-renewable additives with biodegradable compounds. Cellulose plays very important role in this modification. Their low cost and low density associated with high specific mechanical properties represent a good renewable and biodegradable alternative to the most commonly used synthetic reinforcement. The cellulose was modified by using 2-(Tr...

We present a method to increase the stability of DNA nanostructure templates through conformal coating with a nanometer-thin protective inorganic oxide layer created using atomic layer deposition (ALD). DNA nanotubes and origami triangles were coated with ca. 2 nm to ca. 20 nm of Al2O3. Nanoscale features of the DNA nanostructures were preserved after the ALD coating and the patterns are resist...