A new nickel-containing bis(bromobenzyl)salphen monomer suitable for Gilch polymerization was prepared. Reaction with KO(t)Bu in THF-DMF afforded primarily gels, but also soluble, conjugated oligomers that are red-shifted in the absorption spectrum when compared to the monomer. This spectral change, consistent with an enhanced conjugation length, was also compared with a suitable model compound...

Tumor associated carbohydrate antigens (TACAs) are overexpressed on tumor cells, which renders them attractive targets for anti-cancer vaccines. To overcome the poor immunogenicity of TACAs, we designed a polymer platform for antigen presentation by co-delivering TACA and helper T (Th) cell epitope on the same chain. The block copolymer was synthesized by cyanoxyl-mediated free radical polymeri...

Due to recent advances in disease proteomics, many disease-related proteins have been found. It is expected that there will be therapeutically useful proteins among them. However, it is clinically difficult to use most proteins as effective and safe drugs because of their very low stability and pleiotropic actions in vivo. To promote disease proteomic based drug development for protein therapie...

A computer controlled pH meter was developed using simple op-amp circuits. Analog to digital converter (ADC) card was used to acquire the output potential from the op-amp. S9ftware based signal averaging helped in reduction of electrical noise. The instrument was calibrated against pH and ammonia selective electrodes where it followed Nemstian behaviour and was l\Sed in the development of a sim...

We have measured the ratio, r = sigma(S)/sigma(T) of the formation cross section, sigma of singlet and triplet excitons from polarons in pi-conjugated oligomer and polymer films, using a spectroscopic technique we developed recently. We discovered a universal relation between r and the conjugation length (CL): r(-1) depends linearly on CL-1, irrespective of the chain structure. Since r is direc...

Functionalizable monotelechelic polymers are useful materials for chemical biology and materials science. We report here the synthesis of a capping agent that can be used to terminate polymers prepared by ring-opening metathesis polymerization of norbornenes bearing an activated ester. The terminating agent is a cis-butene derivative bearing a Teoc (2-trimethylsilylethyl carbamate) protected pr...

In this paper, we show how composite samples consisting of chains of the semiconducting polymer MEH-PPV embedded into the channels of oriented, hexagonal nanoporous silica glass allow control over energy transfer and exciton migration in the polymer. The composite samples are characterized by two polymer environments: randomly oriented and ®lm-like segments with short conjugationlength outside ...

In the definition of a crossed module $(T,G,rho)$, the actions of the group $T$ and $G$ on themselves are given by conjugation. In this paper, we consider these actions to be arbitrary and thus generalize the concept of ordinary crossed module. Therefore, we get the category ${bf GCM}$, of all generalized crossed modules and generalized crossed module morphisms between them, and investigate som...