Formate stimulates sodium chloride and fluid reabsorption in kidney proximal tubule, however, the exact cellular mechanism of this effect remains unknown. We hypothesized that the primary target of formate is the apical Na/H exchanger. Here we demonstrate that formate directly enhances the apical Na/H exchanger (NHE3) activity in mouse kidney proximal tubule. In the absence of CO2/HCO3, additio...

Cross flow water tube heat exchanger can be designed and made operational using methods of model building and simulation of the system. This paper projects the design and development of a model of cross flow water tube heat-exchanger system, simulation and validation of control analysis of different tuning methods. Feedback and override control system is developed using inputs acquired with the...

An experimental study on the effects of various factors(fin spacing, fin arrangement, air temperature, air humidity, and air velocity) on the frost growth and thermal performance of a finned-tube heat exchanger has been conducted under the frosting condition. It is found that the thermal performance of a heat exchanger is closely related to the blockage ratio of air flow passage due to the fros...

Existing refinery distillation systems are highly energy-intensive, and have complex column configurations that interact strongly with the associated heat exchanger network. An optimisation approach is developed for existing refinery distillation processes. The optimisation framework includes shortcut models developed for the simulation of the existing distillation column, and a retrofit shortc...

Background: The mechanism of hypoxic pulmonary vasoconstriction (HPV) is still debatable. It has been proposed that reactive oxygen species (ROS) might be involved in HPV. However, there is no special transporter for superoxide anion in the cell membrane and it may release from the cells via anion exchanger. Therefore, the aim of this study was to investigate the interaction of ROS and anion ex...

Waste heat recovery is very important, because not only it reduces the expenditure of heat generation, but also it is of high priority in environmental consideration, such as reduction in greenhouse gases. One of the devices is used in waste heat recovery is heat pipe heat exchanger.Anexperimental research has been carried out to investigate the hydrodynamic and thermal performance of a gas...

We have developed a novel procedure for constructing high surface area silver sinter heat exchangers. Our recipe incorporates nylon fibers having a diameter of ∼ 50 μm and thin wires of bulk silver in the heat exchanger. In order to increase the thermal conductance of liquid helium within the heat exchanger, prior to sintering, the nylon fibers are dissolved with an organic acid leaving a netwo...

Heat exchanger system is widely used in chemical plants because it can sustain wide range of temperature and pressure. The main purpose of a heat exchanger system is to transfer heat from a hot fluid to a cooler fluid, so temperature control of outlet fluid is of prime importance. To control the temperature of outlet fluid of the heat exchanger system a conventional PID controller can be used. ...

transport by the human Na ϩ /Ca 2ϩ exchanger expressed in Sf 9 cells. Am. block of the Na ϩ /Ca 2ϩ exchanger was examined in Sf 9 cells expressing the human heart Na ϩ /Ca 2ϩ exchanger (NCX1-NACA1). As predicted from the reported actions of Ni 2ϩ , its application reduced extracellular Na ϩ-dependent changes in intracellular Ca 2ϩ concentration (measured by fluo 3 fluores-cence changes). Howeve...

the objective of the present study is the synthesis of mwcnt-tio2 hybrid nanostructures by solvothermal synthesis method with ticl4 as precursor. the heat transfer enhancement due to the use of mwcnt-tio2 nanofluid was investigated. as-prepared hybrid materials were characterized by x-ray diffraction (xrd) and scanning electron microscopy (sem). the results showed that mwcnts were uniformly dec...