Three cases of craniofacial fibrous dysplasia are reported, all presenting to the ophthalmologist first. They all had ocular complications due either to direct involvement of the orbital bones or to secondary complications. Sphenoidal mucocele is added to the other complications previously reported, and accordingly a classification of the various ways that fibrous dysplasia can affect the ocula...

Figure Legend: Figure 1 Bone Fibrous osteodystrophy in a male F344/N rat from a chronic study. There is replacement of bone by fibrous connective tissue. Figure 2 Bone Fibrous osteodystrophy in a male F344/N rat from a chronic study (same animal as in Figure 1). There is replacement of cortical bone by fibrous connective tissue. Figure 3 Bone Fibrous osteodystrophy in a male F344/N rat from a c...

McCune-Albright syndrome (MAS) is a rare disorder that develops from an activating mutation in the Gs gene. It is characterized by an association with Polyostotic fibrous dysplasia, and precocious puberty, Caf-au-lait pigmentation, and other endocrinopathies that result from the hyperactivity of a variety of endocrine glands. Recently we encountered a patient with MAS with fibrous dysplasia, sk...

In this study, the efficacy of computed tomography (CT) and magnetic resonance imaging (MRI) in the evaluation of craniospinal involvement with polyostotic fibrous dysplasia (PFD) in McCune-Albright syndrome (MAS) and related complications were reviewed. In CT, ground-glass appearance with well-defined borders was seen, with medullary widening and cortical thinning. More rarely, cystic/necrotic...