INTRODUCTION Postoperative nausea and vomiting (PONV) is among the most common distressing complications of surgery under anesthesia. Previous studies have demonstrated that patients who undergo craniotomy have incidences of nausea and vomiting as high as 50-70%. The main purpose of this pilot study is to assess the incidence of PONV by using two different prophylactic regimens in subjects unde...

BACKGROUND Postoperative nausea and vomiting (PONV) are common adverse events with an incidence of up to 80% in high-risk patients. Ramosetron, a selective 5-HT3 receptor antagonist, is widely used to prevent PONV. The purpose of this study was to evaluate the effective dose of ramosetron for the prevention of PONV in high-risk patients. METHODS Fifty-one patients were randomly allocated to 3...

OBJECTIVE To compare the clinical efficacy of acupressure with treatment induced by ondansetron and metoclopramide on reduction of the severity of postoperative nausea and vomiting (PONV) after strabismus surgery. METHODS There were 200 patients with ASA classes I-II, ages 10 to 60 years old, who underwent strabismus surgery that were included in this randomized, prospective, double-blind, pl...

BACKGROUND Pediatric strabismus surgery is commonly associated with higher incidence of postoperative nausea and vomiting (PONV). Mixtures of different classes of antiemetics have been used successfully to decrease the incidence of PONV but there was no agreement on the optimal combination. The aim of this study was to investigate the effect of granisetron, ondansetron, midazolam combination wi...

PURPOSE We compared the prophylactic effects of intravenously administered azasetron (10 mg) and ondansetron (8 mg) on postoperative nausea and vomiting (PONV) in patients undergoing gynecological laparoscopic surgery under general anesthesia. MATERIALS AND METHODS We studied 98 ASA physical status I or II 20-65 years old, female patients, in this prospective, randomized, double blind study. ...

BACKGROUND Despite the development of a new class of antiemetics, postoperative nausea and vomiting (PONV) still remains a frequent and distressing complication. We compared the prophylactic antiemetic effect of administering dexamethasone 5 mg as an adjunct to ramosetron and ondansetron in patients at high-risk for PONV following lumbar spinal surgery. METHODS In this randomized, double-blin...

BACKGROUND Postoperative nausea and vomiting (PONV) is still a common and major complication for surgical patients, which may delay post-anesthetic care unit discharge, prolong hospital stay and thus increase the cost of hospitalization. It is understood that PONV is a multi-factorial outcome and occurs more often with general anesthesia than with other anesthetic methods. Prophylactic administ...

STUDY OBJECTIVE The aim of the study was to compare the antiemetic efficacy and costs associated with 3 different anesthesia regimens used in gynecologic laparoscopy. DESIGN This was a randomized, controlled study. SETTING The study was conducted at a university hospital. PATIENTS We studied 150 ASA physical status I or II patients, undergoing elective gynecologic laparoscopy with general...

Nausea and vomiting is a common and distressing postoperative complication with an incidence of 25-43% after both inpatient and day care surgery1. Patients rate freedom from postoperative nausea and vomiting (PONV) as their most IJBAR (2013) 04 (01) www.ssjournals.com Abstract Purpose: To compare the efficacy of ondansetron-dexamethasone combination with ondansetron alone for prevention of post...

Routine use of a nasogastric (NG) tube has been suggested to prevent postoperative nausea and vomiting (PONV) despite conflicting data. Accordingly, we tested the hypothesis that routine use of a NG tube does not reduce PONV. Our work is based on data from a large trial of 4055 patients initially designed to quantify the effectiveness of combinations of antiemetic treatments for the prevention ...