Upconversion nanocrystals represent a new class of nonlinear optical materials that can convert low energy radiation into higher energy radiation. Recent advances in synthesis techniques have produced nanocrystals with controllable size and color emission as well as novel surface properties that enable such attributes as water solubility and biological functionality. This in turn has led to an ...

A series of 1,3-benzoxazole-4-carbonitriles was synthesized and evaluated for its antifungal activity, solubility, and metabolic stability. Among those compounds, 4-cyano-N,N,5-trimethyl-7-[(3S)-3-methyl-3-(methylamino)pyrrolidin-1-yl]-6-phenyl-1,3-benzoxazole-2-carboxamide (16b) exhibited potent in vitro activity against Candida species, higher water solubility, and improved metabolic stabilit...

This paper reports physicochemical studies in fungal infected galls of Pongamia pinnata. The parameters assayed were Total ash, acid insolubility and water solubility values and extractive values (Alcohol, water and petroleum ether). Fungal infected galls showed significantly higher value of ash, acid insolubility and low water solubility and high extractive values (petroleum ether and water) w...

The purpose of this study was to evaluate the dentin bonding durability of three HEMA-containing one-step self-etch adhesives after one-year water storage and to measure the amounts of their water sorption/solubility. OptiBond All-In-One (OP), Bond Force (BF) and Clearfil S³Bond (S³) were applied to the dentin surfaces according to manufacturers' instructions. Bond strengths to dentin were dete...

Co-delivery approach has been recommended to reduce the amount of each drug and to achieve the synergistic effect for cancer treatment. CUR and SF have antitumor effects, but their application is limited because of their low water solubility and poor oral bioavailability. To improve the bioavailability and solubility of SF and CUR, we performed an innovative co-delivery of SF and CUR with magne...

Background and objectives: Essential oils are used for their flavors and fragrances and their medicinal properties in food, cosmetic, agriculture and pharmaceutical industries. This study was focused on the selection of the best solvent(s) which would increase water solubility of ketone and phenol classes of essential oils. Methods: The solubility of s...

Nanosuspension is a novel drug formulation for the delivery of hydrophobic drugs. The problem medications that are poorly water-soluble and have low bioavailability countered by nanosuspension technology. Solubility significant physiochemical element influences absorption therapeutic effectiveness. Poor aqueous solubility has potential to impair development. technology can improve drug's stabil...

the oil refining industries are using a number of demulsifiers for dewatering and desalination of crude oil but experience has shown that universal demulsifiers can not be produced. each kind of water in oil (w/o) emulsion requires specific by composition demulsifier. in practice, synergetic effect of the interaction between different types of demulsifiers is often sought. for dewatering the w...

Poorly water-soluble compounds are difficult to develop as pesticide products and face great challenges in water-based and environmentally friendly formulation development. In this study, high pressure homogenization combined with lyophilization was adopted to prepare the solid nanodispersions of chlorantraniliprole with poor solubility and high melting point. The mean particle sizes of the sol...