The PoP(Proof of Principle) FFAG accelerator, which was the world first FFAG proton synchrotron, was constructed at KEK. After the first proton beam acceleration of FFAG, we studied various aspects of the PoP FFAG. The observed beam orbit shift during the acceleration was consistent with the simulation result. It was confirmed that the beam intensity increased about five times with multi-bunch ...

The present study aimed to reveal the metabolic alterations of the extracellular matrix (ECM) in uterosacral ligament (USL) with pelvic organ prolapse (POP) and to explore the role of transforming growth factor‑β1 (TGF‑β1) in pathogenesis of POP. For this purpse, 60 participants who underwent hysterectomy for benign indications were enrolled, 30 of which had symptomatic POP (grade II, III or IV...

We discuss the cosmological significance of the transition from the Pop III to Pop II mode of star formation in the early universe, and when and how it may occur in primordial galaxies. Observations that could detect this transition include those of element abundances in metal-poor Galactic halo stars, and of the helium reionization and associated heating of the intergalactic medium. We suggest...

BACKGROUND Point of Purchase (PoP) promotional and advertising activities are a sophisticated tobacco marketing strategy. This study describes tobacco PoP activities in school neighbourhoods and compares PoP activities in retail stores between schools with high and low smoking prevalence. METHODS A cross-sectional study was conducted in 81 randomly selected schools across five provinces. Stud...

This paper introduces the notion of PoP (Policy of Policies) used to define standard policy replacement strategies in a policy-based network. We also propose an architecture to support PoP within PDPs (Policy Decision Points originally defined by the IETF). The notion of PoP, and the proposed architecture allow the automation of the policy replacement task currently manually executed by the net...

BACKGROUND Both Mitofusin 2 (Mfn2) and pelvic organ prolapse (POP) are related to aging. The aim of the present study was to investigate the variations of Mfn2 expression in the uterosacral ligaments of patients with and/or without POP and their correlations with the expression of procollagen. METHODS Fibroblasts were cultured using tissue specimens that were harvested from the uterosacral li...