Breast cancer has long been a significant cause of morbidity and mortality. Mammography is the first-line imaging examination used to detect breast cancer; it has high sensitivity but only moderate specificity. The currently used secondary imaging modalities, sonography and MRI, cannot weed out all the false-positive lesions that mammography identifies as potentially malignant. Further, many pa...

OBJECTIVE To ascertain whether fluorodeoxyglucose positron emission tomography is indicated for clinical staging of superficial cancer, we sought to determine if it accurately classifies tumor (T), regional nodal (N), and distant metastases (M), including distinguishing high-grade dysplasia (Tis) from invasive cancer (T1). METHODS Fifty-eight superficial esophageal cancer patients had preoper...

In this paper, we study 2D cylindrical Positron Emission Tomography (2D PET) sampling. We show that rectangular sampling schemes are more efficient than usual square schemes. 1. PET and sampling 1.1 PET The aim of Positron Emission Tomography (PET) is to map the internal nuclear activity of a patient from exterior measurement. Usually, the patient received some nuclear substance by inhalation o...

The detection of viable myocardium or ischemically injured myocardium with a reversible impairment of contractile function remains clinically important but challenging. Detection of reversible dysfunction and distinction from irreversible tissue injury by positron emission tomography is based on identification of preserved or even enhanced glucose metabolism with F-18 2-fluoro 2-deoxyglucose. R...

BACKGROUND Primary lateral sclerosis (PLS) is a progressive upper motor neuron neurodegenerative condition. The diagnosis is made using clinical history, objective neurological assessment, and exclusion of other neurodegenerative disorders. OBJECTIVE To evaluate the role of fluorodeoxyglucose F18 positron emission tomography and 3-dimensional stereotactic surface projection in the diagnosis o...

Reduced cerebrospinal fluid amyloid-b42 and increased retention of florbetapir positron emission tomography are biomarkers reflecting cortical amyloid load in Alzheimer’s disease. However, these measurements do not always agree and may represent partly different aspects of the underlying Alzheimer’s disease pathology. The goal of this study was therefore to test if cerebrospinal fluid and posit...