BACKGROUND Hypothermia may be beneficial in stroke victims; however, it provokes vigorous shivering. Buspirone and dexmedetomidine each linearly reduce the shivering threshold with minimal sedation and no respiratory depression. This study tested the hypotheses that the combination of buspirone and dexmedetomidine would (1) synergistically reduce the shivering threshold, (2) synergistically red...

Kvadsheim, Petter H., Lars P. Folkow, and Arnoldus Schytte Blix. Inhibition of shivering in hypothermic seals during diving. Am J Physiol Regul Integr Comp Physiol 289: R326–R331, 2005. First published March 10, 2005; doi:10.1152/ajpregu.00708.2004.—The mammalian response to hypothermia is increased metabolic heat production, usually by way of muscular activity, such as shivering. Seals, howeve...

BACKGROUND Shivering during regional anesthesia is a common complication and is related to a decrease in the patient's core body temperature. Previous studies have shown that acupuncture on specific acupoints can preserve core body temperature. The present study evaluated the effect of electroacupuncture in preventing the shivering caused by regional anesthesia. METHODS This prospective and r...

objectives this study evaluates the effects of oral tizanidine on hemodynamic responses during operations and aims to determine the appropriate propofol dosage to maintain anesthesia under bis monitoring. materials and methods a double-blind clinical trial has been performed on 70 candidates for elective abdominal surgery undergoing general anesthesia in educational hospital of ghaem, mashhad, ...

Haman, François. Shivering in the cold: from mechanisms of fuel selection to survival. J Appl Physiol 100: 1702–1708, 2006; doi:10.1152/japplphysiol.01088.2005.—In coldexposed adult humans, significant or lethal decreases in body temperature are delayed by reducing heat loss via peripheral vasoconstriction and by increasing rates of heat production via shivering thermogenesis. This brief review...