Concomitant tumor resistance (CR) is a phenomenon in which a tumor-bearing host is resistant to the growth of secondary tumor implants and metastasis. While former studies have indicated that T-cell dependent processes mediate CR in hosts bearing immunogenic small tumors, the most universal manifestation of CR induced by immunogenic and non-immunogenic large tumors had been associated with an a...

Activity in cortical networks is heterogeneous, sparse and often precisely timed. The functional significance of sparseness and precise spike timing is debated, but our understanding of the developmental and synaptic mechanisms that shape neuronal discharge patterns has improved. Evidence for highly specialized, selective and abstract cortical response properties is accumulating. Singe-cell sti...

In this note we discuss recent progress concerning powerful numbers, raise new questions and show that solutions to existing open questions concerning powerful numbers would yield advancement of solutions to deep, long-standing problems such as Fermat's Last Theorem. This is primarily a survey article containing no new, unpublished results. A powerful number is a positive integer n which is div...

Empowering learners and using powerful techniques are prominent elements in the discourse of adult and vocational education. But what constitutes the elements of what might be considered as powerful teaching? This paper begins by examining the way educators talk about power and then proposes four elements that lie at the heart of powerful teaching; understanding how power dynamics intersect wit...

See article by Akiyama et al. [1] (pages 531 –538) in [3] reported the application of an existing technique, this issue. microdialysis, to estimate interstitial adenosine and its metabolites. Microdialysis, which evolved during the prior Tsuyoshi Akiyama and Toji Yamazaki have reported decade, had largely been limited to studies evaluating that norepinephrine inhibits acetylcholine release from...

Many academics, largely scientists and engineers but also social scientists and management researchers, find that they need more compute power than is provided “on their desk”. If a machine twice as fast is required, then buying one is generally feasible, but this approach rapidly runs into the buffers of price, power consumption, air (or water!) cooling, and sheer availability. The future lies...

Skeleton parallel programming encourages programmers to build a parallel program from ready-made components for which e cient implementations are known to exist, making both the parallel program development and the parallelization process easier. However, programmers often su er from the di culty to choose a proper combination of parallel primitives so as to construct e cient parallel programs....