Depression in prepubertal age group is a relatively rare condition. The presence of life threatening catatonic features call for aggressive treatment. Electro convulsive therapy (ECT) has been described to be effective in these circumstances; however, doubts have been raised about its safety profile. This present case study illustrates the efficacy and safety of ECT in prepubertal catatonia.

OBJECTIVE Identifying and comparinge the physical qualities of Brazilian athletes and practitioners of rhythmic gymnastics. METHODS 125 Brazilian athletes and rhythmic gymnasts practitioners of Rhythmic Gymnastics fromaged 7 to 25 years- old were evaluated. They were divided into the following categories: Different competitive levels (international, national and regional) and pre- and post- m...

Puberty is governed by the secretion of gonadotropin releasing hormone (GnRH), but the roles and identities of upstream neuropeptides that control and time puberty remain poorly understood. Indeed, how various reproductive neural gene systems change before and during puberty, and in relation to one another, is not well-characterized. We detailed the daily pubertal profile (from postnatal day [P...

BACKGROUND Overweight and obesity are considered to be serious public health problems. In pediatric populations, insulin resistance, dyslipidemia, and hypertension associated with obesity occur with increased frequencies. Metformin is an oral anti-hyperglycemic agent that has been demonstrated to be efficacious in the treatment of diabetic and non-diabetic obese adults. A considerable amount of...

Abstract Objectives Puberty is a period of rapid growth and development, the age onset duration puberty may serve as an indicator developmental stress during childhood. In this study, we compare pubertal timing tempo in individuals from two Roman Imperial cemetery sites, integrating biological social factors to better understand differences their possible connection Early Life Stress (ELS) peri...

We present a case of testicular dermoid cyst that was treated with transinguinal excision of the testicular cyst with preservation of the healthy testicular parenchyma. We have reviewed the literature for clinical features and therapeutic approach in benign cystic tumors in the pre-pubertal testis.

BACKGROUND In many countries age at pubertal onset has declined substantially. Relatively little attention has been paid to how this decline may affect adolescent behaviours such as substance use, violence and unprotected sex and consequently impact on public health. METHODS In the UK, two opportunistic samples (aged 16-45 years), paper-based (n = 976) and online (n = 1117), examined factors ...

OBJECTIVE To compare clinical signs of puberty onset in daughters of pre-eclampsia and normotensive pregnancies. DESIGN Population based follow-up study. METHODS In a cohort of 120 daughters of pre-eclampsia pregnancies and 203 daughters of pregnancies without pre-eclampsia, pubic hair growth and breast development were assessed at 11, 12 and 13 years of age by Tanner scores and by self-ass...

The liver plays a central role in metabolism and produces important hormones. Hepatic estrogen receptors and the release of insulin-like growth factor 1 (IGF1) are critical links between liver function and the reproductive system. However, the role of liver in pubertal development is not fully understood. To explore this question, we applied transcriptomic analyses to liver samples of pre- and ...

We aimed to explore the association between family conflict and HPA axis activity, especially with respect to the potential modulating effect of puberty. A total of 205 adolescents and 244 adult parents were recruited. Family conflict was assessed by the family conflict subscale of the Family Environmental Scale and serial salivary cortisol was measured in all participants. A marginally lower A...