The retina is the most oxygen consuming tissue of the body. Rod and cone photoreceptors efficiently carry out visual cascades, which are energetically costly processes. Data has recently been published that suggests that the metabolic support to phototransduction in the rod outer segment (OS) may originate directly in the OS, which is able to conduct aerobic metabolism. This oxygen-handling act...

BACKGROUND AND PURPOSE Retinal vasculopathy is commonly found with complaint of burred vision by ophthalmologist and closely related to asymptomatic cerebrovascular disease. The purpose of this study was to evaluate patients with microvascular retinopathy by ultrasound sonography of neck carotid artery and to find high risk group for stroke at outpatient of ophthalmology with associated retinop...

Prematurity and preterm stressors severely affect the development of infants born before 37 weeks gestation, with increasing effects seen at earlier gestations. Although mortality rates have declined due to advances in neonatal care, disability rates, especially middle-income settings, continue grow. With MRI imaging technology, there has been a focus on safely brain better understand its disco...

Retinopathy of prematurity is a vasoproliferative retinopathy occurring primarily, but not exclusively, in premature infants. The condition is a major cause of pediatric blindness in developed countries. Although acute retinopathy of prematurity regresses spontaneously for more than 90% of infants, a chronic or late proliferative phase follows in some eyes whereby tractional retinal detachments...

Comprehensive oxygen management, focused on avoiding hyperoxia and repeated episodes of hypoxia-hyperoxia in very low birth weight infants, has been successfully used for the reduction of retinopathy of prematurity. Building on this experience, the Comprehensive Oxygen Management for the Prevention of Retinopathy of Prematurity quality improvement initiative was developed to facilitate the spre...

BACKGROUND Systemic diseases and their treatment influence aggressive posterior retinopathy of prematurity. CASE CHARACTERISTICS A premature infant with aggressive posterior retinopathy of prematurity underwent laser treatment with a favourable outcome. She was started on oral sidenafil citrate for pulmonary hypertension. Ten days later she developed neovascularization within the lasered reti...

The objective of this study is to review the current state and role of computer-assisted analysis in diagnosis of plus disease in retinopathy of prematurity. Diagnosis and documentation of retinopathy of prematurity are increasingly being supplemented by digital imaging. The incorporation of computer-aided techniques has the potential to add valuable information and standardization regarding th...