Background: Karyotype analysis has been the standard and reliable procedure for prenatal cytogenetic diagnosis since the 1970s. However, the major limitation remains requirement for cell culture, resulting in a delay of as much as 14 days to get the test results.CGH array technology has proven to be useful in detecting causative genomic imbalances or genetic mutations in as many as 15% of child...

Prenatal whole exome sequencing (WES) and genome (WGS) have not been adopted into routine obstetrical practice due to high cost suspected low diagnostic yield. However, the actual yield of these methods in pregnancies with specific prenatal findings is known. The goal this study determine whether types complications are associated actionable postnatal WES/WGS results. This a case control compar...

Congenital talipes equinovarus is a common anomaly which can now be diagnosed prenatally on a routine ultrasound scan at 20 weeks of gestation. Prenatal counselling is increasingly offered to parents with affected fetuses, but it is difficult to counsel parents if there is a chance that the fetus may not have talipes. Our study correlates the prenatal ultrasound findings of 14 infants diagnosed...

External male genitalia have rarely been evaluated on fetal ultrasound. Apart from visualization of the penis for sex determination, there are no specific instructions or recommendations scientific societies. This study aimed to review current knowledge about prenatal diagnosis scrotum and internal structures, with discussion regarding technical aspects clinical management. We conducted an arti...

Congenital diaphragmatic hernia (CDH) is a rare condition. The reported incidence of intrathoracic renal ectopia due to CDH is also rare. A right-sided thoracic kidney is much less common due to the location of the liver. Isolated intrathoracic kidney is usually asymptomatic and diagnosed incidentally on chest imaging. The authors report on a 21days old female infant with late-presenting right ...

Both three-dimensional (3D) and four-dimensional (4D) ultrasound have improved our knowledge regarding the develop ment of the embryo and fetus and of a great number of fetal anomalies. The great achievement in the field of 3D/4D ultrasound is HDlive technology. This technology is a novel ultrasound technique that improves the 3D/4D images. Furthermore, recent advanced 3D technology has produce...

Current two-dimensional (2D) ultrasonic marker measurements are inherent with intra- and inter-observer variability limitations. The objective of this paper is to investigate the performance of conventional 2D ultrasonic marker measurements and proposed programmable interactive three-dimensional (3D) marker evaluation. This is essentially important to analyze that the measurement on 3D volumetr...

Objective: To assess the value of adding three-dimensional (3D) power Doppler (as a diagnostic technique) to grayscale in the prenatal diagnosis of placenta accreta. Material and Methods: One hundred pregnant women with persistent placenta previatotalis (after 28 weeks' gestation) were prospectively enrolled into this study. Gray-scale transabdominal ultrasound was performed to detect loss of t...

Title of dissertation: EMPIRICAL ESSAYS ON DEVELOPMENT ECONOMICS IN CHINA Lingsheng Meng, Doctor of Philosophy, 2010 Dissertation directed by: Professor Mark Duggan Department of Economics My dissertation is composed of three essays on Development Economics in China. The first chapter, co-authored with Hongbin Li, evaluates the impact of the 8-7 Plan, the second wave of China’s poverty alleviat...