Integration of engineered musculoskeletal tissues with adjacent native tissues presents a significant challenge to the field. Specifically, the avascularity and low cellularity of cartilage elicit the need for additional efforts in improving integration of neocartilage within native cartilage. Self-assembled neocartilage holds significant potential in replacing degenerated cartilage, though its...

Let X,, , X, be a sequence of independent and identically distributed random variables with an unknown underlying continuous cumulative distribution function F. Relative to this unknown distribution function suppose one would like to test a null hypothesis concerning the goodness of fit of F to some distribution function using symmetric functions of sample spacings. In some applications the nul...

June 1, 2010 Version 0.7-0 Date 2010-04-07 Title Non-supervised Regional Frequency Analysis Author Alberto Viglione Maintainer Alberto Viglione Depends stats, graphics Description A collection of statistical tools for objective (non-supervised) applications of the Regional Frequency Analysis methods in hydrology. The package refers to the index-value method and, mo...

It seems to be a platitude that belief is governed by a norm of truth. Isn’t the point of belief to believe truths ? Isn’t it a requirement of believing that we should not believe falsehoods? A number of philosophers, however, deny this. Although they recognise that there is an intimate connection between belief and truth, they reject the idea that this connection is normative. Indeed, they tel...

MESERVEY, R., 1971. The coastline fit of Africa and South America. Palaeogeography, Palaeoclimatol., Palaeoecol., 9: 233-243. It has become axiomatic that the pre-drift reconstruction of Africa and South America is to be made by fitting together the continental shelves. Although this procedure is very plausible, actually the detailed fit of the coastlines is better than that of the shelves and ...

Bone atrophy caused by stress-shielding may cause serious complications for the long-term fixation of hip stems. In particular, uncemented total hip arthroplasty is threatened by this problem, because the stems are usually larger and, as a consequence, stiffer than those of cemented implants. In the present study, the effects of fit and bonding characteristics of femoral hip stems were investig...