Pressurized aerosols of sympathomimetic drugs are widely used in the treatment of bronchial asthma. The efficacy of this form of treatment is diminished in a number of patients by difficulties in coordination between the aerosol actuation and the inhalation. In order to improve the intrapulmonary deposition of terbutaline, an extension tube has been adapted to the regular pressurized aerosol de...

Two-stage pressurized anaerobic digestion is a promising technology. This technology integrates in one process biogas production with upgrading and pressure boosting for grid injection. To investigate whether the efficiency of this novel system could be further increased, a water scrubbing system was integrated into the methanogensis step. Therefore, six leach-bed reactors were used for hydroly...

In subduction zones, elevated pore fluid pressure, generally linked to metamorphic dehydration reactions, has a profound influence on the mechanical behavior of the plate interface and forearc crust through its control on effective stress. We use seismic noise-based monitoring to characterize seismic velocity variations following the 2012 Nicoya Peninsula, Costa Rica earthquake [M w (moment mag...

To evaluate the food safety effect of NaCl-free processing, acidification, smoking and high pressure in QDS processed dry-cured ham, 3 ham types (non-acidified smoked, acidified, and acidified smoked) were produced according to a standard (-S) and a new NaCl-free (-F) process. Slices were spiked with Listeria monocytogenes and Salmonella enterica (three strains each, <2 log CFU/g), dried by the...

High hydrostatic pressure (HHP) has been investigated and industrially applied to extend shelf life of meat-based products. Traditional ham packaged under microaerophilic conditions may sometimes present high lactic acid bacteria population during refrigerated storage, which limits shelf life due to development of unpleasant odor and greenish and sticky appearance. This study aimed at evaluatin...

Evidence from light microscopy (principally polarization microscopy) has demonstrated that hydrostatic pressure can reversibly inhibit mitosis by rapidly depolymerizing the spindle fiber microtubules. We have confirmed this finding in ultrastructural studies of mitotic HeLa cells incubated at 37 degrees C and pressurized at 680 atm (10,000 psi). Althouth there are many spindle microtubules in t...

the acute coronary syndrome due to the left main coronary artery (lmca) thrombosis is a clinically rare and catastrophic event.   we describe a young man ( smoker, alcoholic, and drug abuser) with a history of recent surgery and typical chest pain who had non-occlusive lmca thrombosis in coronary angiography. the thrombosis was successfully treated with two 180 µ/kg intracoronary boluses of ept...

Pressurized hot water extraction (PHWE) has become a popular green extraction method for different classes of compounds present in numerous kinds of matrices such as environmental, food and botanical samples. PHWE is also used in sample preparation to extract organic contaminants from foodstuff for food safety analysis and soils/sediments for environmental monitoring purposes. The main paramete...