The interaction of bondholder's conversion and issuer's call in a convertible bond leads to a game option model between the two counterparties. Like typical pricing models for corporate debts, the fair value of a convertible bond is highly dependent on issuer's credit risk, tax benefits of coupons and other structural features. The convertible bond pricing models in the literature can be catego...

As significant increases in the costs of cancer drugs cause financial difficulties for many U.S. patients, some oncologists suggest that changes in pricing policies at the federal and state levels are inevitable.

BACKGROUND The pricing mechanism of orphan drugs appears arbitrary and has been referred to as a "black box". Therefore, the aim of this study is to investigate how drug- and disease-specific variables relate to orphan drug prices. Additionally, we aim to explore if certain country-specific pricing and reimbursement policies affect the price level of orphan drugs. METHODS Annual treatment cos...

Any QoS scheme must be designed from the perspective of pricing policies and service level agreements (SLAs). Although there has been enormous amount of research in designing mechanisms for delivering QoS, its applications has been limited due to the missing link between QoS, SLA and pricing. Therefore the pricing policies in practice are very simplistic (fixed price per unit capacity with fixe...

Organized by three distinguished members of the JBS Editorial Board – Marc Bickle, PhD, of the Max Planck Institute of Molecular Cell Biology and Genetics (Germany); Hakim Djaballah, PhD, of Institut Pasteur Korea (South Korea); and Lorenz Martin Mayr, PhD, of AstraZeneca (UK) – this special issue demonstrates how RNAi is enjoying a revival of popularity and is increasingly being applied to dis...

This study models fundamental features of current and prospective policies encouraging adoption of residential photovoltaic (PV) systems. A key finding is that time-of-day (ToD) pricing can enhance or worsen the economics of PV systems. Moreover, increased responsiveness of electricity demand to its price diminishes the effectiveness of ToD pricing in the absence of net metering, but does not a...

This paper studies the optimal pricing problem for firms using two types of restrictions. Linear programming techniques will be used to derive the optimal pricing policies under three different scenarios, namely the nested restrictions, mutually exclusive restrictions and the general case. For the first two scenarios, there exists an optimal pricing policy consisting of at most four price level...