نتایج جستجو برای: primary amide

تعداد نتایج: 655059  

Journal: :iranian journal of basic medical sciences 0
elham hakimizadeh physiology-pharmacology research centre, rafsanjan university of medical sciences, rafsanjan, iran department of biology, science and research branch, islamic azad university, tehran, iran shahrbanoo oryan department of biology, science and research branch, islamic azad university, tehran, iran akbar hajizadeh moghaddam department of biology, faculty of basic sciences, university of mazandaran, babolsar, iran ali shamsizadeh physiology-pharmacology research centre, rafsanjan university of medical sciences, rafsanjan, iran ali roohbakhsh physiology-pharmacology research centre, rafsanjan university of medical sciences, rafsanjan, iran

objective(s) fatty acid is amide hydrolase which reduce endogenous anandamide. transient receptor potential vanilloid-1 (trpv1) channels have been reported to have a role in the modulation of anxiety-like behaviors in rodents. in the present study, the effects of either endocannabinoid system or trpv1 channels and their possible interaction on anxiety-like behaviors of the rats were explored. m...

Journal: :Applied and environmental microbiology 2012
Jun Zhang Jin-Gang Yin Bao-Jian Hang Shu Cai Jian He Shun-Gui Zhou Shun-Peng Li

The bacterial isolate Paracoccus sp. strain FLN-7 hydrolyzes amide pesticides such as diflubenzuron, propanil, chlorpropham, and dimethoate through amide bond cleavage. A gene, ampA, encoding a novel arylamidase that catalyzes the amide bond cleavage in the amide pesticides was cloned from the strain. ampA contains a 1,395-bp open reading frame that encodes a 465-amino-acid protein. AmpA was ex...

Journal: :FEBS letters 1990
G Richter R Göke B Göke R Arnold

Specific binding of 125I-labelled GLP-1(7-36)amide to rat lung membranes was dependent upon time and temperature and was proportional to membrane protein concentration. Binding was inhibited in a concentration-dependent manner by unlabelled GLP-1(7-36)amide consistent with the presence of a single class of binding sites with a dissociation constant (Kd) of 1.67 +/- 0.29 nmol/l. GLP-1(1-36)amide...

1999
Christopher Cox Harald Wack Thomas Lectka

The carbonyl oxygen atom of the amide functional group is universally believed to be the thermodynamically preferred site of protonation in amides;[1] however, N protonation has been proposed to play a key role in biologically important reactions of peptides and proteins such as acid-catalyzed peptide hydrolysis[2] and cis ± trans isomerization about the CÿN bond.[3] Extensive research into the...

Journal: :American journal of respiratory and critical care medicine 2001
E Vara J Arias-Díaz C Garcia J L Balibrea E Blázquez

To determine the influence of glucagon-like peptides on the secretion of human pulmonary surfactant, we used human type II pneumocytes. In these cells, GLP-1(7-36) amide and exendin-4 stimulated phosphatidylcholine secretion (PC) and cAMP formation in a concentration-dependent manner; these effects were reversed by exendin(9-39). No changes were observed with other related peptides. The mechani...

Journal: :The journal of physical chemistry. A 2005
Tomoyuki Hayashi Wei Zhuang Shaul Mukamel

An anharmonic vibrational Hamiltonian for the amide I, II, III, and A modes of N-methyl acetamide (NMA), recast in terms of the 19 components of an external electric field and its first and second derivative tensors (electrostatic DFT map), is calculated at the DFT(BPW91/6-31G(d,p)) level. Strong correlations are found between NMA geometry and the amide frequency fluctuations calculated using t...

Journal: :Journal of biotechnology 1994
N Layh A Stolz J Böhme F Effenberger H J Knackmuss

Bacteria were enriched from soil samples with succinate as a carbon source and racemic naproxen nitrile [2-(6-methoxy-2-naphthyl)propionitrile] as sole source of nitrogen. Since naproxen nitrile was only poorly soluble in water media amended with different water-immiscible organic phases were used for the enrichments. With pristane (2,6,10,14-tetramethylpentadecane) as the organic phase two bac...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1978
K Tatemoto V Mutt

The presence or absence of peptide hormones in tissue extracts may in certain cases be demonstrated by exposing the extracts to conditions under which characteristic fragments of the polypeptide molecule in question are formed and then analyzing for such fragments. An approximate quantitation of the hormones may also be achieved thereby. In the present work the COOH-terminal fragments of polype...

Journal: :Natural toxins 1992
R J Petroski R G Powell K Clay

Stipa robusta (= Stipa vaseyi) is a perennial grass found in certain areas of the southwestern United States. It is commonly known as sleepygrass, as horses that ingest this grass may become profoundly somnolent or stuporous for periods of time lasting up to several days. In an attempt to determine the active principle(s), fractionation of a methanolic extract of sleepygrass infected with an Ac...

Journal: :Peptides 1997
J A Veenstra F G Noriega R Graf R Feyereisen

Three allatostatins have been isolated from the mosquito Aedes aegypti. These peptides have the following structures: Ser-Pro-Lys-Tyr-Asn-Phc-Gly-Leu-amide, Leu-Pro-His-Tyr-Asn-Phe-Gly-Leu-amide, and Arg-Val-Tyr-Asp-Phe-Gly-Leu-amide. A cDNA encoding these peptides was isolated from an abdominal ganglia cDNA library and sequenced. It was found to encode two additional allatostatins: Ala-Ser-Ala...

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