A polypeptide fraction isolated from the urine of normotensive subjects lowers the blood pressure (BP) in a rabbit bioassay (mean BP decrease 33.8% +/- 0.6%, SEM). Patients with primary hypertension exhibit reduced or no activity (mean BP decrease 8.8% +/- 1.2%). In contrast, patients with secondary forms of hypertension show activity like normotensives (mean BP decrease 33.4% +/- 1.0%). The re...

STUDY OBJECTIVES Although in situ thrombosis is a prominent finding in lung vessels from patients with primary and secondary pulmonary hypertension, to our knowledge, plasma coagulation factors that might contribute to a hypercoagulable state have not been fully investigated. We hypothesized that the local coagulation environment in the lung vasculature is important to progression if not initia...

abstractintroduction: athough a controversial issue, the metabolic syndrome (ms) is known to by be related to certain genetic and lifestyle factors such as hypertension. the object of this study is to evaluate the prevalence of ms and its association to hypertension among diabetic patients with and without hypertension, in the fatemeh zahra hospital in najafabad, iran. materials and methods: th...