Extramammary Paget’s disease (EMPD) is a rare form of primary or secondary intraepithelial adenocarcinoma typically presenting within the fifth through seventh decades life. Though cases EMPD localized to scrotum are not associated with underlying malignancy, evaluation dermal and angiolymphatic invasion in conjunction pertinent laboratory investigations, e.g., serum CEA, essential rule out mal...

Primary esophageal melanoma is an extremely rare malignancy with estimated prevalence of 0.0036 cases per million year. The prognosis the disease unfavorable, in 30-40% patients metastases are detected at time diagnosis, generally accepted approaches to treatment currently insufficiently developed. article presents review literature and describes clinical case a patient primary

Purpose. In the clinical work-up of a retroperitoneal mass, the diagnosis of soft tissue sarcoma is often not considered. Incidence rates of various malignant and benign retroperitoneal tumours were studied to determine the incidence of soft tissue sarcoma in comparison with other neoplasms in the retroperitoneal space.Method. Nation-wide data on retroperitoneal tumours, collected prospectively...

BACKGROUND Metastatic malignancy to the thyroid gland is generally uncommon due to an unfavourable local thyroid micro-environment which impairs the ability of metastatic cells to settle and thrive. Metastases to the thyroid gland have however been reported to occur occasionally particularly if there has been disruption to normal thyroid tissue architecture. CASE PRESENTATION We report a pati...

BACKGROUND The diagnostic yield was evaluated of percutaneous image-guided tissue biopsy of hepatic lesions identified on computed tomography performed for staging of a primary malignancy, and it was determined how often the biopsy result was unexpectedly negative, benign, or secondary to a second unknown malignancy. METHODS In a retrospective investigation from 1998 through 2008, 580 patient...

Gastric carcinoma usually metastasizes to liver, peritoneum, lymphnodes, ovary, lung and brain. But gastric malignancy metastasizing to cervix is extremely rare and even rarest in young patients. Reaching to the primary site of hidden gastric malignancy on a cervical biopsy was very interesting in present case. Distinction of primary cervical malignancy to metastasis is very important for clini...

BACKGROUND Light microscopic evaluation of cell morphology in preparations from urine or bladder washing containing exfoliated cells is a standard and primary method for the detection of bladder cancer and also malignancy from other parts of the urinary tract. The cytopathologic examination is a valuable method to detect an early recurrence of malignancy or new primary carcinoma during the foll...