New data from the NIH reveal that the scientific return on its sponsored research reaches a maximum at around $400,000 of annual support per principal investigator. We discuss the implications of this 'sweet spot' for funding policy, and propose that the NIH should limit both the minimum and maximum amount of funding per researcher.

Award Number: W81XWH-11-1-0307 TITLE: Biocompatible, Biodegradable, and Enzymatic-Cleavable MRI Contrast Agents for Early Detection of Bone Metastatic Breast cancer PRINCIPAL INVESTIGATOR: Xuli Wang, Ph.D. CONTRACTING ORGANIZATION: University of Utah Salt Lake City, Utah 84112-8930 REPORT DATE: April 2013 TYPE OF REPORT: Final PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort D...

This study was funded by National Institutes of Health grant no. K08 AI-073525 (S.R.D.), by a fellowship from the Consejo Nacional para Ciencia y Tecnología of the Mexican federal government (S.G.R.), and by a fellowship from the Brazilian government agencies Coordenação de Aperfeiçoamento de Pessoal de Nível Superior and Conselho Nacional de Desenvolvimento Científico e Tecnológico (L.G.B.G.).

TITLE: Brain Vulnerability to Repeated Blast Overpressure and Polytrauma PRINCIPAL INVESTIGATOR: Joseph B. Long, Ph.D. CONTRACTING ORGANIZATION: The Geneva Foundation Tacoma, WA 98402 REPORT DATE: November 2013 TYPE OF REPORT: Final PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATEMENT: Approved for public release; distribution un...

1 Final report for AOARD/ ITC-PAC Grant 114071 “Silica & Germanate Glass High Power Fiber Laser Sources” Prepared: January 2014 PI and Co-PI information: Principal Investigator: Prof Tanya Monro Co investigators: A/Prof Heike Ebendorff-Heidepriem, A/Prof David Lancaster, Dr David Ottaway Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, Australia Period of Investi...

Award Number: W81XWH-11-1-0736 TITLE: Inhibition of Th17 Cell Differentiation as a Treatment for Multiple Sclerosis PRINCIPAL INVESTIGATOR: Annalisa D’Andrea, PhD CONTRACTING ORGANIZATION: SRI International, Menlo Park,CA,94025 REPORT DATE: October 2013 TYPE OF REPORT: Final Report PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort Detrick, Maryland 21702-5012 DISTRIBUTION STATE...

W81XWH-10-1-0404 TITLE: Receptive Vocabulary Knowledge in Low-Functioning Autism as Assessed by Eye Movements, Pupillary Dilation, and Event-Related Potentials PRINCIPAL INVESTIGATOR: Barry Gordon, M.D., Ph.D. CONTRACTING ORGANIZATION: The Johns Hopkins University Baltimore, MD 21218 REPORT DATE: June 2013 TYPE OF REPORT: Annual PREPARED FOR: U.S. Army Medical Research and Materiel Command Fort...

1 Invited position paper for the IEEE Symposium on Reliable Distributed Systems (SRDS), Panel on Reliability and Security of Distributed and Mobile Systems. Supported by the Aerospace Institute, The Aerospace IRAD Corporate Research Initiative, the DARPA Cyber Panel program, and other DoD programs. 2 The author has been a DARPA Principal Investigator on a number of networking and information as...

NNIN REU Site: Nano Research Facility, Washington University in St. Louis, St. Louis, MO NNIN REU Principal Investigator: Prof. Samuel Achilefu, Optical Radiology Laboratory, Mallinckrodt Institute of Radiology, Washington University in St. Louis School of Medicine NNIN REU Mentor: Dr. Rui Tang, Optical Radiology Laboratory, Mallinckrodt Institute of Radiology, Washington University in St. Loui...

NNIN REU Site: Nanotechnology Research Center, Georgia Institute of Technology, Atlanta, GA NNIN REU Principal Investigator: Dr. Ravi V. Bellamkonda, Neurological Biomaterials and Cancer Therapeutics Lab, Department of Biomedical Engineering, Georgia Institute of Technology NNIN REU Mentor: Dr. S.Balakrishna Pai, Neurological Biomaterials and Cancer Therapeutics Lab, Department of Biomedical En...