OBJECTIVES To evaluate the adequacy of as-needed (prn) dosing of narcotics during the acute postoperative period following laryngectomy and to evaluate the role of nurses' interpretation and implementation of narcotic orders in postoperative pain management. STUDY DESIGN A retrospective review of the medical records of 37 patients who underwent laryngectomy at the University of Oklahoma. The ...

In this paper, the performance of cognitive radio (CR) code divisionmultiple access (CDMA) networks is analyzed in the presence of receive beamforming at the base stations (BSs). More precisely, we analyze, through simulations, the performance achievable by a CR user, with and without spectrum sensing, in a three-cell scenario. Uplink communications are considered. Three different schemes for s...

The stringent response (SR) is a regulatory mechanism that enables bacteria to adapt to nutrient stress through the production of the alarmone (p)ppGpp. The aim of the current study was to understand how the SR affects the antifungal (AF) activity of Pseudomonas chlororaphis PA23. Two SR mutants were generated, PA23relA and PA23relAspoT, that no longer produced (p)ppGpp. Both mutants exhibited ...

Mumps virus-neutralizing antibodies are believed to be the most predictable surrogate marker of protective immunity. However, assays used to detect neutralizing antibodies, such as the plaque reduction neutralization (PRN) assay, are labor- and time-intensive and consequently are often supplanted by the more rapid and inexpensive enzyme immunoassay (EIA) technique. For virus infections for whic...

Abstract Background Bordetella pertussis is a gram-negative bacterium causing the highly contagious respiratory infection in over 151 000 individuals annually worldwide. A tetanus/diphtheria/pertussis (Tdap) vaccine combined with CpG 1018 adjuvant (Tdap-1018) may induce higher antibody titers than existing aluminum-adjuvanted Tdap vaccines used as booster adults. Methods In this randomized, act...

Abstract Postoperative recovery depends on a complex interplay of patient-related factors which mobility is an essential part. The aim this study to evaluate correlations between perioperative physical activity, quality life, and postoperative nursing workload in colorectal surgery. A prospective was used assess footsteps, workload. Number footsteps recorded from preoperative day 5 3. Patients ...

Reliable signal acquisition with low computational complexity is an important design objective for the evolution of global navigation satellite systems (GNSS). Most GNSS signals consist long pseudorandom noise (PRN) codes whose expensive in terms memory, computation time, and energy. As these resources are particularly scarce emerging mass-market user segment, cyclostationary pilot short PRN ...

This study exatnined patterns of psychotropic medication use among 120 participants with intellectual disabilities (ID) who used to live in facilities and now reside in community-based settings in Ontario. There were significantly more participants taking psychotropic medication in the community (83.30/0) than in the facility (74.2%). Of those who showed change, 4.2% were taking medication in t...

The response surface metamodel is a useful sequential methodology for approximating the relationship between the input variables and the output response in computer simulation. Several strategies have been proposed to increase the accuracy of the estimation of the metamodel. In the current paper, we introduce an effective pseudo-random number (PRN) assignment strategy with Box-Behnken design to...

The results of randomized controlled clinical trials of ranibizumab for the treatment of age-related macular degeneration established a new standard of care with the prospect of improved vision in many patients. Subsequent trials have explored different strategies to increase response rates and reduce treatment frequency. This review analyzes the key clinical trial data for ranibizumab on the b...