prodigiosin

Haeyoung Jeong Joung Han Yim Choonghwan Lee Sang-Haeng Choi Yon Kyoung Park Sung Ho Yoon Cheol-Goo Hur Ho-Young Kang Dockyu Kim Hyun Hee Lee Kyun Hyang Park Seung-Hwan Park Hong-Seog Park Hong Kum Lee Tae Kwang Oh Jihyun F. Kim

Harmful algal blooms, caused by rapid growth and accumulation of certain microalgae in the ocean, pose considerable impacts on marine environments, aquatic industries and even public health. Here, we present the 7.2-megabase genome of the marine bacterium Hahella chejuensis including genes responsible for the biosynthesis of a pigment which has the lytic activity against a red-tide dinoflagella...

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A GntR family transcriptional regulator (PigT) controls gluconate-mediated repression and defines a new, independent pathway for regulation of the tripyrrole antibiotic, prodigiosin, in Serratia.

Journal: :Microbiology 2005

Peter C Fineran Lee Everson Holly Slater George P C Salmond

Biosynthesis of the red, tripyrrole antibiotic prodigiosin (Pig) by Serratia sp. ATCC 39006 (39006) is controlled by a complex regulatory network involving an N-acyl homoserine lactone (N-AHL) quorum-sensing system, at least two separate two-component signal transduction systems and a multitude of other regulators. In this study, a new transcriptional activator, PigT, and a physiological cue (g...

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