The frequency of spontaneous premature rupture of membranes (PROM) was determined in the pregnancies of 1,848 white mothers and their singleton infants, born at the University of Kansas Medical Center between April 1975 and April 1978. The frequency of PROM increased significantly from a low of 34/707 (4.8 percent) among low-risk mothers, to 40/444 (9.0 percent) among mothers smoking one to 60 ...

BACKGROUND The clinical significance and management of preterm premature rupture of membranes (PPROM) remains a topic of a controversy. Although PROM is associated with a low rate of complications, PPROM may lead to significant neonatal and maternal morbidity. METHODS We performed a retrospective study of 714 women who presented to Jiangsu Province Hospital with third trimester PPROM or PROM ...

background: preterm premature rupture of membranes (pprom) occurs in 3% of pregnancies and 30-40% of preterm labors are related to this problem. early diagnosis of pprom is very important due to its impact on pregnancy outcomes. objective: to determine the diagnostic value of aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in vaginal fluid for the diagnosis of preterm...

Prediction of metabolic changes that result from genetic or environmental perturbations has several important applications including diagnosing metabolic disorders and discovering novel drug targets. A cardinal challenge in obtaining accurate predictions is the integration of transcriptional regulatory networks with the corresponding metabolic network. We propose a new method called Probabilist...

Abstract Process discovery is an important area in the field of process mining. To help advance this area, a contest (PDC) has been set up, which allows us to compare different approaches. At moment writing, there have three instances PDC: 2016, 2017, and 2019. This paper introduces winning contribution PDC 2019, called Log Skeleton Visualizer. visualizer uses novel type models log skeletons. I...

Premature rupture of membranes (PROM), defined as breakage the amniotic sac prior to delivery, complicates 2–4% pregnancies, leads one-third preterm births, and increases risk perinatal mortality morbidity in survivors. In situ bioprinting enables fabrication 3D structures directly for tissue repair or reconstruction living animals, but is challenging perform subaqueous narrow space where fetal...

Process mining techniques allow for extracting information from event logs. For example, the audit trails of a workflow management system or the transaction logs of an enterprise resource planning system can be used to discover models describing processes, organizations, and products. Traditionally, process mining has been applied to structured processes. In this paper, we argue that process mi...

OBJECTIVES To compare the effectiveness, safety of immediate induction with PGE(2) gel and expectant management in terms of maternal and fetal outcome in term PROM. METHODS 100 women were randomized to group A, immediate induction and group B expectant management. RESULTS Spontaneous vaginal deliveries were more in group B. CS and operative vaginal deliveries were more in group A. CONCLUS...